De l’application de teinture capillaire à l’unité de soins intensifs : une réaction sévère à la para-phénylènediamine

IF 0.3 4区 医学
F.Z. El Fatoiki, Z. Mouhsine, Y. Mahdar, F. Hali, S. Chiheb
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引用次数: 0

Abstract

Para-phenylenediamine (PPD), a common allergen in hair dyes and black henna tattoos, is typically responsible for allergic contact dermatitis and, rarely, systemic reactions like anaphylaxis. We report the case of a 22-year-old female with no significant medical history who developed pruritic eyelid edema and respiratory distress 24 hours after using a PPD-containing hair dye. She had prior exposure to black henna without issues. Clinical examination revealed erythematous plaques with vesicles and eyelid edema. Respiratory symptoms included dyspnea, tachycardia, and dysphonia. The patient required intensive care, receiving nebulized and intramuscular adrenaline, followed by corticosteroids. Patch testing confirmed a positive reaction to PPD. This case highlights the rare but possible coexistence of immediate and delayed hypersensitivity reactions to PPD, reflecting a complex and potentially severe immunologic mechanism. It emphasizes the importance of PPD regulation, patch testing for diagnosis, and prevention of repeated exposures.
从染发到重症监护室:对对苯二胺的严重反应
对苯二胺(PPD)是染发剂和黑色指甲花纹身中常见的过敏原,通常会导致过敏性接触性皮炎,很少会引起过敏反应等全身性反应。我们报告一例22岁女性无明显病史,在使用含ppd的染发剂24小时后出现瘙痒性眼睑水肿和呼吸窘迫。她之前接触过黑色指甲花,没有问题。临床检查发现红斑斑块伴小泡及眼睑水肿。呼吸系统症状包括呼吸困难、心动过速和发音困难。患者需要重症监护,接受雾化和肌肉注射肾上腺素,随后使用皮质类固醇。斑贴试验证实对PPD有阳性反应。本病例强调PPD的即时和延迟超敏反应罕见但可能共存,反映了复杂且潜在严重的免疫机制。它强调了PPD调控、斑贴检测诊断和预防重复暴露的重要性。
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来源期刊
Revue Francaise d Allergologie
Revue Francaise d Allergologie Medicine-Immunology and Allergy
自引率
33.30%
发文量
349
期刊介绍: La Revue Française d''Allergologie : un véritable forum pour faire connaître des travaux originaux et permettre la diffusion de l''information auprès de toutes les spécialités concernées par les pathologies allergiques. La Revue Française d''Allergologie (8 numéros par an) est au carrefour de nombreuses spécialités - dermatologie, pédiatrie, ORL, pneumologie, ophtalmologie, médecine interne - qui, toutes, ont à traiter des maladies allergiques. Les symptômes des allergies fondés sur des mécanismes communs sont le plus souvent associés et se succèdent chez un même patient. En forte progression depuis 20 ans, les maladies allergiques sont dans l''attente de perfectionnements et d''avancées thérapeutiques qui permettront aux nombreux patients qui en sont atteints de mieux vivre avec leurs allergies. La Revue Française d''Allergologie se veut donc un véritable forum de discussions et d''échanges entre tous les spécialistes confrontés aux pathologies
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