Risk factors associated with postoperative complications in pediatric thyroidectomy: A single-center Vietnamese experience

IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
Quy Xuan Ngo , Duong The Le , Duy Quoc Ngo
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Abstract

Background

Pediatric thyroid carcinoma presents unique surgical challenges, with potentially significant postoperative complications affecting long-term developmental outcomes. This investigation aimed to evaluate postoperative complications following thyroidectomy in pediatric patients and identify associated prognostic factors within a high-volume Vietnamese surgical center.

Methods

A retrospective analysis was conducted on 112 pediatric patients (≤18 years) who underwent thyroidectomy for differentiated thyroid carcinoma between January 2014 and January 2023. Primary outcomes included the incidence and characteristics of postoperative complications, particularly focusing on recurrent laryngeal nerve injury and hypoparathyroidism. Risk factors were evaluated using univariate and multivariate analyses.

Results

The cohort predominantly comprised female patients (68.8 %), with a mean age of 15.2 ± 2.7 years. Papillary thyroid carcinoma constituted 96.4 % of cases. Total thyroidectomy was performed in 70.5 % of patients, with central compartment lymph node dissection in 83.0 %. Transient recurrent laryngeal nerve dysfunction occurred in 16.1 % of cases, while transient hypocalcemia affected 24.1 % of patients. No permanent complications were observed. Multivariate analysis identified total thyroidectomy as an independent predictor of both complications (p < 0.05). Central compartment nodal metastatic burden (>5 nodes) significantly correlated with transient recurrent laryngeal nerve dysfunction (p < 0.05).

Conclusions

Low complication rates espicially the absence of permanent complications support the safety of thyroidectomy in pediatric single-center in Vietnam. The study underscores the importance of expertise in managing pediatric thyroid carcinoma, while identifying specific risk factors that may inform surgical decision-making and patient counseling.
儿童甲状腺切除术术后并发症的相关危险因素:越南单中心经验
儿童甲状腺癌具有独特的手术挑战,其潜在的重大术后并发症会影响长期发育结局。本研究旨在评估儿童甲状腺切除术后的并发症,并在越南一个大容量外科中心确定相关的预后因素。方法回顾性分析2014年1月至2023年1月间因分化型甲状腺癌行甲状腺切除术的112例(≤18岁)患儿。主要结局包括术后并发症的发生率和特点,特别是喉返神经损伤和甲状旁腺功能减退。使用单因素和多因素分析评估危险因素。结果本组以女性患者为主(68.8%),平均年龄15.2±2.7岁。甲状腺乳头状癌占96.4%。70.5%的患者行甲状腺全切除术,83.0%的患者行中央室淋巴结清扫。一过性喉返神经功能障碍发生率为16.1%,而一过性低钙发生率为24.1%。无永久性并发症。多变量分析发现甲状腺全切除术是两种并发症的独立预测因子(p <;0.05)。中央室淋巴结转移负荷(>;5个淋巴结)与短暂性喉返神经功能障碍(p <;0.05)。结论越南儿童单中心甲状腺切除术并发症发生率低,无永久性并发症,安全性高。该研究强调了管理儿童甲状腺癌专业知识的重要性,同时确定了可能为手术决策和患者咨询提供信息的特定风险因素。
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来源期刊
CiteScore
3.20
自引率
6.70%
发文量
276
审稿时长
62 days
期刊介绍: The purpose of the International Journal of Pediatric Otorhinolaryngology is to concentrate and disseminate information concerning prevention, cure and care of otorhinolaryngological disorders in infants and children due to developmental, degenerative, infectious, neoplastic, traumatic, social, psychiatric and economic causes. The Journal provides a medium for clinical and basic contributions in all of the areas of pediatric otorhinolaryngology. This includes medical and surgical otology, bronchoesophagology, laryngology, rhinology, diseases of the head and neck, and disorders of communication, including voice, speech and language disorders.
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