Orofacial myofunctional and anthropometric characteristics of children with and without microcephaly: a case-control study.

IF 2.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE
Journal of Applied Oral Science Pub Date : 2025-07-07 eCollection Date: 2025-01-01 DOI:10.1590/1678-7757-2024-0473
Andréa Monteiro Correia Medeiros, Gabriela Rodrigues Dourado Nobre, Geyse do Espírito Santo Rezende, Íkaro Daniel de Carvalho Barreto, Jonan Emi Valencia Cardenas, Sarah Catarina Santos Nascimento, Anna Luiza Dos Santos Matos, Asenate Soares de Matos Pereira, Ricardo Queiroz Gurgel, Giédre Berretin-Felix
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引用次数: 0

Abstract

Objective: This study aimed to describe and compare morphofunctional orofacial aspects between subjects with and without Zika virus-related microcephaly.

Methodology: This was a descriptive, cross-sectional, case-control study with both qualitative and quantitative components. All subjects were born between 2015 and 2016, during the Zika virus outbreak in the Northeast region of Brazil. A total of 48 children were included: 24 with Zika-related microcephaly (MG) and 24 without the condition (CG). We performed the Preliminary Expanded Protocol of Orofacial Myofunctional Evaluation with Scores (OMES-E) for all subjects. Orofacial anthropometric measurements were obtained from 36 of the 48 participants, including 18 from the MG and 18 from the CG.

Results: We found lower swallowing efficiency scores in children with microcephaly aged 13-18 months. Significant differences (p<.001) were found between the MG and CG for scores related to the face, cheeks, and total stomatognathic functions. When stratified by age group, differences (p<.001) were found in total scores between MG and CG subjects in the age groups up to 24 months. We found lower scores in the 13-18-month group with microcephaly for swallowing efficiency: 1.3 (SD: .8) versus 5.3 (SD: 1.2); and in the 19-24-month group; for bite: 1 (SD: 0) and 3.9 (SD: .3), and 1.9 (SD: 2.7) and 9.5 (SD: .9); in addition to facial changes: 9.8 (SD: 1.2) and 11.8 (SD: .6). Differences were found in anthropometric orofacial measurements for the upper third of the face (d=-1.215, p<.001) (MGCG) (d=-.679, p<.001).

Conclusion: Subjects with microcephaly had altered orofacial myofunction, especially related to swallowing and chewing difficulties in early ages.

Abstract Image

有和没有小头畸形的儿童的口面部肌功能和人体测量特征:一项病例对照研究。
目的:本研究旨在描述和比较患有和未患有寨卡病毒相关小头畸形的受试者的形态功能口面部方面。研究方法:这是一项描述性、横断面、病例对照的定性和定量研究。所有研究对象都出生在2015年至2016年巴西东北部地区寨卡病毒爆发期间。共纳入48名儿童:24名患有寨卡相关小头畸形(MG), 24名无该病(CG)。我们对所有受试者进行了口面部肌功能评分初步扩展方案(oes - e)。48名参与者中的36名获得了口面部人体测量数据,其中18名来自MG, 18名来自CG。结果:我们发现13-18月龄小头畸形患儿吞咽效率评分较低。显著性差异(pCG) (d=-。结论:小头畸形患者的口面部肌功能发生改变,尤其是早期吞咽和咀嚼困难。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Applied Oral Science
Journal of Applied Oral Science 医学-牙科与口腔外科
CiteScore
4.80
自引率
3.70%
发文量
46
审稿时长
4-8 weeks
期刊介绍: The Journal of Applied Oral Science is committed in publishing the scientific and technologic advances achieved by the dental community, according to the quality indicators and peer reviewed material, with the objective of assuring its acceptability at the local, regional, national and international levels. The primary goal of The Journal of Applied Oral Science is to publish the outcomes of original investigations as well as invited case reports and invited reviews in the field of Dentistry and related areas.
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