{"title":"Explainable AI for time series prediction in economic mental health analysis.","authors":"Ying Yang, Lifen Wen, Li Li","doi":"10.3389/fmed.2025.1591793","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The integration of Explainable Artificial Intelligence (XAI) into time series prediction plays a pivotal role in advancing economic mental health analysis, ensuring both transparency and interpretability in predictive models. Traditional deep learning approaches, while highly accurate, often operate as black boxes, making them less suitable for high-stakes domains such as mental health forecasting, where explainability is critical for trust and decision-making. Existing <i>post-hoc</i> explainability methods provide only partial insights, limiting their practical application in sensitive domains like mental health analytics.</p><p><strong>Methods: </strong>To address these challenges, we propose a novel framework that integrates explainability directly within the time series prediction process, combining both intrinsic and post-hoc interpretability techniques. Our approach systematically incorporates feature attribution, causal reasoning, and human-centric explanation generation using an interpretable model architecture.</p><p><strong>Results: </strong>Experimental results demonstrate that our method maintains competitive accuracy while significantly improving interpretability. The proposed framework supports more informed decision-making for policymakers and mental health professionals.</p><p><strong>Discussion: </strong>This framework ensures that AI-driven mental health screening tools remain not only highly accurate but also trustworthy, interpretable, and aligned with domain-specific knowledge, ultimately bridging the gap between predictive performance and human understanding.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1591793"},"PeriodicalIF":3.1000,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241169/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fmed.2025.1591793","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: The integration of Explainable Artificial Intelligence (XAI) into time series prediction plays a pivotal role in advancing economic mental health analysis, ensuring both transparency and interpretability in predictive models. Traditional deep learning approaches, while highly accurate, often operate as black boxes, making them less suitable for high-stakes domains such as mental health forecasting, where explainability is critical for trust and decision-making. Existing post-hoc explainability methods provide only partial insights, limiting their practical application in sensitive domains like mental health analytics.
Methods: To address these challenges, we propose a novel framework that integrates explainability directly within the time series prediction process, combining both intrinsic and post-hoc interpretability techniques. Our approach systematically incorporates feature attribution, causal reasoning, and human-centric explanation generation using an interpretable model architecture.
Results: Experimental results demonstrate that our method maintains competitive accuracy while significantly improving interpretability. The proposed framework supports more informed decision-making for policymakers and mental health professionals.
Discussion: This framework ensures that AI-driven mental health screening tools remain not only highly accurate but also trustworthy, interpretable, and aligned with domain-specific knowledge, ultimately bridging the gap between predictive performance and human understanding.
期刊介绍:
Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
In addition to papers that provide a link between basic research and clinical practice, a particular emphasis is given to studies that are directly relevant to patient care. In this spirit, the journal publishes the latest research results and medical knowledge that facilitate the translation of scientific advances into new therapies or diagnostic tools. The full listing of the Specialty Sections represented by Frontiers in Medicine is as listed below. As well as the established medical disciplines, Frontiers in Medicine is launching new sections that together will facilitate
- the use of patient-reported outcomes under real world conditions
- the exploitation of big data and the use of novel information and communication tools in the assessment of new medicines
- the scientific bases for guidelines and decisions from regulatory authorities
- access to medicinal products and medical devices worldwide
- addressing the grand health challenges around the world