Pediatric Health Risks Among Children of Female Military Aviation Officers.

IF 0.9 4区医学 Q4 BIOPHYSICS

Aerospace medicine and human performance Pub Date : 2025-05-01 DOI:10.3357/AMHP.6418.2025

Matthew Royall, Ian S Sorensen, Christopher M Stark, Madeline Dorr, Sandra Salzman, Elizabeth Hisle-Gorman, Nicole Dobson, Jill Brown, Apryl Susi, Brian H Huggins, Cade M Nylund

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引用次数: 0

Abstract

Introduction: Female aviators and aircrew face unique occupational exposures, including noise, whole-body vibrations, toxic chemicals, intermittent hypoxia, and high gravitational forces. We evaluated associations between maternal occupations as aviators and aircrew during pregnancy and adverse pediatric health outcomes.

Methods: We conducted a retrospective cohort study of children born to female U.S. military officers from October 2002 to December 2019. Exposure was defined as the mother serving in an aviation or aircrew occupation at time of birth. Adverse health outcomes were identified by International Classification of Diseases codes. Cox proportional hazards regression was performed, adjusting for maternal age at delivery, maternal race and ethnicity, and marital status. A post hoc power analysis was performed.

Results: The study included 18,637 female officers. There were 1144 children of fixed-wing aviation officers and 25,889 children of non-aviation officers. There was decreased risk of adverse neurodevelopmental outcomes [hazard ratio (HR), 0.81; 95% confidence interval (CI), 0.68-0.95], speech delay (HR, 0.72; 95% CI, 0.59-0.89), and other and unspecified congenital anomalies (HR, 0.74; 95% CI, 0.60-0.90) for children of aviators. There was no increased risk for any of the adverse pediatric outcomes. Five outcomes had sufficient sample size to detect significance.

Discussion: Although this study suggests that children of military officers in aviation careers do not have an increased risk for adverse pediatric outcomes, it was underpowered and cannot conclusively imply safety of maternal aviation occupational exposures during pregnancy. Further research must evaluate how prenatal exposure to flight affects subsequent pediatric health outcomes. Royall M, Sorensen IS, Stark CM, Dorr M, Salzman S, Hisle-Gorman E, Dobson N, Brown J, Susi A, Huggins BH, Nylund CM. Pediatric health risks among children of female military aviation officers. Aerosp Med Hum Perform. 2025; 96(5):386-391.

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女航空军官子女的儿科健康风险。

导语：女性飞行员和机组人员面临着独特的职业暴露，包括噪音、全身振动、有毒化学物质、间歇性缺氧和高重力。我们评估了母亲在怀孕期间担任飞行员和机组人员的职业与儿童不良健康结局之间的关系。方法：我们对2002年10月至2019年12月期间美国女性军官所生的孩子进行了回顾性队列研究。暴露被定义为母亲在孩子出生时从事航空或机组工作。不良健康后果由国际疾病分类代码确定。进行Cox比例风险回归，调整产妇分娩年龄、产妇种族和民族以及婚姻状况。进行事后功率分析。结果：该研究包括18,637名女军官。固定翼航空军官的子女有1144人，非航空军官的子女有25 889人。不良神经发育结局的风险降低[危险比（HR）， 0.81；95%可信区间（CI）， 0.68-0.95]，言语延迟(HR, 0.72；95% CI, 0.59-0.89)，以及其他未指明的先天性异常(HR, 0.74；95% CI, 0.60-0.90)。没有任何儿童不良结局的风险增加。5个结果有足够的样本量来检测显著性。讨论：虽然这项研究表明，军官的子女在航空职业生涯中没有增加儿童不良结局的风险，但它的力量不足，不能最终暗示母亲在怀孕期间航空职业暴露的安全性。进一步的研究必须评估产前暴露于飞行如何影响随后的儿科健康结果。Royall M, Sorensen IS, Stark CM, Dorr M, Salzman S, Hisle-Gorman E, Dobson N, Brown J, Susi A, Huggins BH, Nylund CM。航空女军官子女的儿科健康风险。航空航天Med Hum Perform. 2025；96(5): 386 - 391。

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来源期刊

Aerospace medicine and human performance PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -MEDICINE, GENERAL & INTERNAL

CiteScore

1.10

自引率

22.20%

发文量

272

期刊介绍： The peer-reviewed monthly journal, Aerospace Medicine and Human Performance (AMHP), formerly Aviation, Space, and Environmental Medicine, provides contact with physicians, life scientists, bioengineers, and medical specialists working in both basic medical research and in its clinical applications. It is the most used and cited journal in its field. It is distributed to more than 80 nations.