Noninvasive Left Ventricular Pressure-Strain Loop for Assessment of Myocardial Work in Hemodialysis in Patients With Chronic Kidney Disease

IF 1.4 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques Pub Date : 2025-07-11 DOI:10.1111/echo.70243

Yunxiang Miao, Lin Fan, Bingyuan Zhou, Yuping Liao, Ying Yin

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引用次数: 0

Abstract

Objective

To explore the value of a novel echocardiographic measure—left ventricular pressure-strain loop (LV-PSL) for assessment of patients with chronic kidney disease by comparing the changes before and after hemodialysis (HD).

Methods

A total of 117 patients undergoing regular hemodialysis were recruited. Global longitudinal strain (GLS) combined with cuff blood pressure measurement is used to calculate the global work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE). The differences in echocardiographic parameters before and after hemodialysis on the same day were compared. Additionally, 50 healthy individuals were included as the control group.

Results

Compared with the control group, both the pre-HD and post-HD groups exhibited significantly lower GLS and GWE (pre-HD: p = 0.006 and p = 0.000, respectively; post-HD: p = 0.000 and p = 0.000, respectively). In contrast, the pre-HD group had significantly higher values in PSD, GWI, GCW, and GWW (p = 0.000 for PSD and GWW; p = 0.001 for GWI and GCW). Notably, the post-HD group also had higher values in PSD and GWW compared to the control group (p = 0.000 for both), while no significant differences were observed in GWI and GCW between the post-HD and control groups (p = 0.247 and p = 0.134, respectively).

Conclusions

The LV-PSL parameters are capable of effectively assessing myocardial work in HD patients. Moreover, these parameters offer novel reference indicators for evaluating volume load and left ventricular myocardial function in HD patients.

Abstract Image

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无创左心室压力-应变环评估慢性肾病血液透析患者心肌工作

目的通过比较血液透析（HD）前后左心室压力-应变环（LV-PSL）的变化，探讨超声心动图测量左心室压力-应变环（LV-PSL）对慢性肾病患者的评价价值。方法选取定期血液透析患者117例。采用全局纵向应变（GLS）与袖带血压测量相结合的方法计算全局功指数（GWI）、全局建设性功（GCW）、全局浪费功（GWW）和全局工作效率（GWE）。比较当日血液透析前后超声心动图参数的差异。另外，50名健康个体作为对照组。结果与对照组相比，hd前组和hd后组GLS和GWE均显著降低(hd前：p = 0.006和p = 0.000；后hd：分别p = 0.000和p = 0.000)。相比之下，hd前组的PSD、GWI、GCW和GWW值显著升高(PSD和GWW p = 0.000；GWI和GCW的p = 0.001)。值得注意的是，hd后组的PSD和GWW值也高于对照组（p = 0.000），而GWI和GCW值在hd后组与对照组之间无显著差异（p = 0.247和p = 0.134）。结论LV-PSL参数能有效评价HD患者心肌功能。这些参数为评价HD患者的容量负荷和左室心肌功能提供了新的参考指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques 医学-心血管系统

CiteScore

2.40

自引率

6.70%

发文量

211

审稿时长

3-6 weeks

期刊介绍： Echocardiography: A Journal of Cardiovascular Ultrasound and Allied Techniques is the official publication of the International Society of Cardiovascular Ultrasound. Widely recognized for its comprehensive peer-reviewed articles, case studies, original research, and reviews by international authors. Echocardiography keeps its readership of echocardiographers, ultrasound specialists, and cardiologists well informed of the latest developments in the field.