Factors influencing decision-making on opportunistic salpingo-oophorectomy for ovarian cancer prevention in women with gastrointestinal cancers undergoing intra-abdominal surgery

IF 1.3 Q3 OBSTETRICS & GYNECOLOGY

Gynecologic Oncology Reports Pub Date : 2025-07-10 DOI:10.1016/j.gore.2025.101800

Jaekyung Bae , Uisuk Kim , Sokbom Kang

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引用次数: 0

Abstract

Objective

To assess the attitudes of women with non-gynecologic cancers undergoing intra-abdominal surgery toward opportunistic salpingo-oophorectomy (OSO) for ovarian cancer prevention, and to identify factors influencing their decision-making regarding prophylactic surgery.

Methods

From July 2022 to August 2023, a questionnaire-based survey was conducted among women aged 40 years or older scheduled for intra-abdominal surgery for gastric or colorectal cancer at the National Cancer Center Korea. After providing information on ovarian cancer risk and laparoscopic salpingo-oophorectomy, including its benefits and potential risks, data were collected on participants’ cancer history, menopausal status, education level, income, family history of cancer, concerns about ovarian cancer, and perceptions of cancer treatment. Quality of life and menopausal symptoms were assessed using the EuroQol 5 Dimensions 3 Levels questionnaire (EQ-5D-3L) and the Menopause Rating Scale.

Results

Overall, 60.2 % of the respondents (59 out of 98) were willing to undergo OSO at the time of their surgery. The most common reason for declining OSO was a lack of concern about ovarian cancer (21/39, 53.8 %), followed by concerns about potential declines in quality of life (13/39, 33.3 %). Personal or familial cancer history, concerns about cancer treatment, perceived risk of ovarian cancer, menopausal symptoms, and overall quality of life did not significantly influence the decision to accept or refuse OSO.

Conclusions

The choice to undergo OSO appears to be driven more by personal perception of ovarian cancer risk and worries about postoperative quality of life than by measurable menopausal symptoms, current health-related quality of life, or previous cancer-related experiences. These findings offer important guidance for the development of OSO-centered ovarian cancer prevention strategies.

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影响经腹腔手术的胃肠癌患者择机性输卵管-卵巢切除术预防卵巢癌决策的因素

目的了解行腹腔手术的非妇科肿瘤患者对机会性输卵管-卵巢切除术（OSO）预防卵巢癌的态度，并探讨影响其预防性手术决策的因素。方法：从2022年7月至2023年8月，在韩国国立癌症中心对40岁及以上计划进行腹部手术治疗胃癌或结直肠癌的女性进行问卷调查。在提供了卵巢癌风险和腹腔镜输卵管-卵巢切除术的信息，包括其益处和潜在风险之后，收集了参与者的癌症病史、更年期状况、教育水平、收入、癌症家族史、对卵巢癌的担忧以及对癌症治疗的看法等数据。使用EuroQol 5维度3水平问卷（EQ-5D-3L）和更年期评定量表评估生活质量和更年期症状。结果总体而言，60.2%的受访者（98人中有59人）在手术时愿意接受OSO。OSO下降的最常见原因是缺乏对卵巢癌的关注（21/39,53.8%），其次是对生活质量潜在下降的担忧（13/39,33.3%）。个人或家族癌症病史、对癌症治疗的担忧、卵巢癌的感知风险、更年期症状和总体生活质量对接受或拒绝卵巢移植的决定没有显著影响。结论：选择OSO似乎更多是由个人对卵巢癌风险的认知和对术后生活质量的担忧所驱动，而不是由可测量的更年期症状、当前健康相关的生活质量或先前的癌症相关经历所驱动。这些发现为制定以oso为中心的卵巢癌预防策略提供了重要的指导。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Gynecologic Oncology Reports OBSTETRICS & GYNECOLOGY-

CiteScore

2.00

自引率

0.00%

发文量

183

审稿时长

41 days

期刊介绍： Gynecologic Oncology Reports is an online-only, open access journal devoted to the rapid publication of narrative review articles, survey articles, case reports, case series, letters to the editor regarding previously published manuscripts and other short communications in the field of gynecologic oncology. The journal will consider papers that concern tumors of the female reproductive tract, with originality, quality, and clarity the chief criteria of acceptance.