Repetitive transcranial magnetic stimulation at low frequency for the treatment of fibromyalgia. Results from the first treatment cohort at the brainwave clinic.

IF 2.5 Q2 CLINICAL NEUROLOGY

Frontiers in pain research (Lausanne, Switzerland) Pub Date : 2025-06-25 eCollection Date: 2025-01-01 DOI:10.3389/fpain.2025.1558175

Elliot Nation, Anushka Irani, Stephanie Barrett

{"title":"Repetitive transcranial magnetic stimulation at low frequency for the treatment of fibromyalgia. Results from the first treatment cohort at the brainwave clinic.","authors":"Elliot Nation, Anushka Irani, Stephanie Barrett","doi":"10.3389/fpain.2025.1558175","DOIUrl":null,"url":null,"abstract":"Objective: To assess the clinical effectiveness of low-frequency repetitive transcranial magnetic stimulation (rTMS) in treating fibromyalgia (FM) in a real-world setting.Methods: Eighteen adults diagnosed with FM received 20 sessions of low-frequency rTMS over the right dorsolateral prefrontal cortex (DLPFC). Pain and symptom burden were assessed using the Numerical Rating Scale (NRS), Fibromyalgia Impact Questionnaire (FIQ), Sheehan Disability Scale (SDS), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI). Outcomes were compared using paired t-tests.Results: Statistically significant improvements were observed in NRS, FIQ, BDI, and BAI. A non-significant trend towards reduced disability (SDS) was observed. No serious adverse effects were reported.Conclusion: Low-frequency rTMS over the DLPFC shows promise as a safe and effective treatment for FM, improving pain, mood, and impact of FM symptoms, with a trend towards improving disability. Further research with larger cohorts is needed.","PeriodicalId":73097,"journal":{"name":"Frontiers in pain research (Lausanne, Switzerland)","volume":"6 ","pages":"1558175"},"PeriodicalIF":2.5000,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237879/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in pain research (Lausanne, Switzerland)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3389/fpain.2025.1558175","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: To assess the clinical effectiveness of low-frequency repetitive transcranial magnetic stimulation (rTMS) in treating fibromyalgia (FM) in a real-world setting.

Methods: Eighteen adults diagnosed with FM received 20 sessions of low-frequency rTMS over the right dorsolateral prefrontal cortex (DLPFC). Pain and symptom burden were assessed using the Numerical Rating Scale (NRS), Fibromyalgia Impact Questionnaire (FIQ), Sheehan Disability Scale (SDS), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI). Outcomes were compared using paired t-tests.

Results: Statistically significant improvements were observed in NRS, FIQ, BDI, and BAI. A non-significant trend towards reduced disability (SDS) was observed. No serious adverse effects were reported.

Conclusion: Low-frequency rTMS over the DLPFC shows promise as a safe and effective treatment for FM, improving pain, mood, and impact of FM symptoms, with a trend towards improving disability. Further research with larger cohorts is needed.

Abstract Image

查看原文本刊更多论文

低频重复经颅磁刺激治疗纤维肌痛。脑电波诊所第一个治疗队列的结果。

目的：探讨低频重复经颅磁刺激（rTMS）治疗纤维肌痛（FM）的临床效果。方法：18名确诊为FM的成年人在右背外侧前额叶皮层（DLPFC）接受20次低频rTMS。采用数值评定量表（NRS）、纤维肌痛影响问卷（FIQ）、Sheehan残疾量表（SDS）、Beck抑郁量表（BDI）和Beck焦虑量表（BAI）对疼痛和症状负担进行评估。结果采用配对t检验进行比较。结果：NRS、FIQ、BDI、BAI均有统计学意义的改善。观察到残疾减少（SDS）的非显著趋势。没有严重的不良反应报告。结论：低频rTMS在DLPFC上显示出安全有效的治疗FM的希望，改善疼痛、情绪和FM症状的影响，并有改善残疾的趋势。需要进行更大规模的进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊