Correlation between Acetowhite Examination, Dermoscopy, and Histopathology in Patients with Anogenital Warts.

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL
Qaira Anum, Vesri Yossy, Nellia Fonna
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引用次数: 0

Abstract

Anogenital warts, caused by human papillomavirus (HPV) infection, are characterized by papular lesions in the anogenital region. Acetowhite examination and dermoscopy are non-invasive methods that might aid in confirming the clinical diagnosis. This study aimed to evaluate the diagnostic accuracy of acetowhite examination and dermoscopy compared to histopathological findings in anogenital warts. This cross-sectional study included patients diagnosed with anogenital warts at Dr. M. Djamil Padang Hospital (Padang, Indonesia) from January 2023 to December 2023. Using the purposive sampling method, 62 lesions from 54 patients (28 men and 26 women) aged 16-59 years were analyzed. Each lesion underwent acetowhite examination, dermoscopy, and histopathological examination. Descriptive analyses were performed on subject characteristics and dermoscopic features, while sensitivity and specificity were calculated using a 2×2 table. The majority of lesions were found in the perianal area in men (44%) and the vulva in women (39%). The acetowhite examination demonstrated a sensitivity of 91% but lacked specificity and negative predictive value (NPV), indicating limitations in identifying negative results. In contrast, dermoscopy exhibited 100% sensitivity and specificity. The findings indicated that both acetowhite examination and dermoscopy were effective diagnostic tools for anogenital warts, with dermoscopy providing exceptional accuracy. These non-invasive methods could potentially reduce the need for more invasive histopathological procedures. Dermoscopy, in particular, serves as a sensitive and specific adjunct tool, offering reliable diagnostic capabilities that can enhance clinical practice.

肛门生殖器疣患者乙酰白检查、皮肤镜检查和组织病理学的相关性。
由人乳头瘤病毒(HPV)感染引起的肛门生殖器疣,其特征是肛门生殖器区域的丘疹病变。乙酰白检查和皮肤镜检查是非侵入性的方法,可能有助于确认临床诊断。本研究的目的是评估白蛋白检查和皮肤镜检查的诊断准确性,比较组织病理学结果在肛门生殖器疣。这项横断面研究包括2023年1月至2023年12月在Dr. M. Djamil Padang医院(印度尼西亚Padang)诊断为肛门生殖器疣的患者。采用目的抽样方法,对年龄16 ~ 59岁的54例患者(男28例,女26例)62个病灶进行分析。每个病灶均行乙酰白检查、皮肤镜检查和组织病理学检查。对受试者特征和皮肤镜特征进行描述性分析,同时使用2×2表计算敏感性和特异性。大多数病变发生在男性的肛周(44%)和女性的外阴(39%)。乙酰白检查的敏感性为91%,但缺乏特异性和阴性预测值(NPV),表明在识别阴性结果方面存在局限性。相比之下,皮肤镜检查显示100%的敏感性和特异性。研究结果表明,醋酸白检查和皮肤镜检查是诊断肛门生殖器疣的有效工具,皮肤镜检查提供了卓越的准确性。这些非侵入性方法可能潜在地减少更多侵入性组织病理学检查的需要。特别是皮肤镜检查,作为一种敏感和特殊的辅助工具,提供可靠的诊断能力,可以加强临床实践。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Iranian Journal of Medical Sciences
Iranian Journal of Medical Sciences MEDICINE, GENERAL & INTERNAL-
CiteScore
3.20
自引率
0.00%
发文量
84
审稿时长
12 weeks
期刊介绍: The Iranian Journal of Medical Sciences (IJMS) is an international quarterly biomedical publication, which is sponsored by Shiraz University of Medical Sciences. The IJMS intends to provide a scientific medium of com­muni­cation for researchers throughout the globe. The journal welcomes original clinical articles as well as clinically oriented basic science re­search experiences on prevalent diseases in the region and analysis of various regional problems.
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