Association between age at menarche and infertility in Tabari cohort population: a population-based case-control study.

IF 1.6 Q2 MULTIDISCIPLINARY SCIENCES

BMC Research Notes Pub Date : 2025-07-09 DOI:10.1186/s13104-025-07357-2

Marzieh Zamaniyan, Mina Esmaeili, Sepideh Peivandi, Shamim Khorshidian, Mobina Gheibi, Monirolsadate Hosseini Tabaghdehi, Mahmood Moosazadeh, Erfan Ghadirzadeh

引用次数: 0

Abstract

Objective: There are conflicting results regarding the association between age at menarche (AAM) and infertility in different nations. Thus, this study aimed to determine this relationship in a cohort of northern Iranian population (Tabari Cohort Study).

Results: The mean menarche age for the case and control groups was 13.48 ± 1.63 and 13.67 ± 1.72, respectively (P: 0.060). The rate of infertility in women of early, normative, and late menarche were 56.3%, 50.4% and 30.4% respectively. The results of the adjusted logistic regression analysis showed that women with early AAM (OR: 3.36, 95% CI: 1.48-7.63, P: 0.004) and normative AAM (OR: 2.90, 95% CI: 1.42-5.90, P: 0.003) had higher odds for infertility compared to females with late menarche with a trend toward higher risk in earlier AAM.

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Tabari队列人群初潮年龄与不孕症之间的关系：一项基于人群的病例对照研究。

目的：在不同的国家，关于月经初潮年龄（AAM）与不孕症之间的关系存在矛盾的结果。因此，本研究旨在确定伊朗北部人群队列中的这种关系（Tabari队列研究）。结果：病例组和对照组的平均月经初潮年龄分别为13.48±1.63岁和13.67±1.72岁（P: 0.060）。初潮早、初潮正常、初潮晚的不孕率分别为56.3%、50.4%、30.4%。调整后的logistic回归分析结果显示，早期AAM （OR: 3.36, 95% CI: 1.48-7.63, P: 0.004）和标准AAM （OR: 2.90, 95% CI: 1.42-5.90, P: 0.003）的女性与月经初潮较晚的女性相比，不孕的几率更高，且早期AAM的风险更高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Research Notes Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

3.60

自引率

0.00%

发文量

363

审稿时长

15 weeks

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