Event Classification in Heterostructured Scintillators With Limited Readout Information Using Neural Networks

IF 4.6 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Carsten Lowis;Fiammetta Pagano;Marco Pizzichemi;Karl-Josef Langen;Karl Ziemons;Etiennette Auffray
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Abstract

To improve coincidence time resolution (CTR) in time-of-flight positron emission tomography (TOF-PET), various approaches have been explored, including the use of novel materials like heterostructured scintillators. These scintillators combine different materials with complementary properties like Bismuth Germanate for its high detection efficiency and EJ232 for fast timing. By layering these materials on a micrometer scale, energy sharing between them becomes possible, enabling fast timing, while maintaining high detection efficiency. For TOF-PET applications, scalable electronics are essential. While earlier models characterized heterostructured scintillators in analog, single-pixel setups, the digital and scalable systems required for full positron emission tomography (PET) scanners present additional challenges due to increased signal complexity. In this study, we explored neural networks to characterize heterostructured scintillators using parameters available in scalable systems. We trained one neural network to identify photoelectric events and another one to estimate the amount of energy sharing between the two materials. The method demonstrated promising results using multiple combinations of the aforementioned parameters, with prediction accuracy for photoelectric events ranging from 91.6% to 96.8%, and a mean average error in the energy sharing estimation between 7.7 and 43.9 keV. This suggests the potential application of heterostructured scintillators in scalable readout electronics for full TOF-PET systems.
基于神经网络的有限读出信息异质闪烁体事件分类
为了提高飞行时间正电子发射断层扫描(TOF-PET)的符合时间分辨率(CTR),人们探索了各种方法,包括使用异质结构闪烁体等新型材料。这些闪烁体结合了不同的材料,具有互补的特性,如德国酸铋的高检测效率和EJ232的快速定时。通过在微米尺度上分层这些材料,它们之间的能量共享成为可能,实现快速定时,同时保持高检测效率。对于TOF-PET应用,可扩展的电子设备是必不可少的。虽然早期的模型在模拟、单像素设置中具有异质结构闪烁体的特征,但由于信号复杂性的增加,全正电子发射断层扫描(PET)扫描仪所需的数字和可扩展系统面临着额外的挑战。在这项研究中,我们探索了神经网络,利用可扩展系统中可用的参数来表征异质结构闪烁体。我们训练了一个神经网络来识别光电事件,另一个神经网络来估计两种材料之间的能量共享量。利用上述参数的多种组合,该方法对光电事件的预测精度在91.6% ~ 96.8%之间,能量共享估计的平均误差在7.7 ~ 43.9 keV之间。这表明异质结构闪烁体在全TOF-PET系统的可扩展读出电子器件中的潜在应用。
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来源期刊
IEEE Transactions on Radiation and Plasma Medical Sciences
IEEE Transactions on Radiation and Plasma Medical Sciences RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
8.00
自引率
18.20%
发文量
109
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