The effectiveness of mobile health applications on the quality of life of hypertension patients: A systematic review and meta-analysis

IF 3.4 3区医学 Q1 HEALTH POLICY & SERVICES

Health Policy and Technology Pub Date : 2025-07-03 DOI:10.1016/j.hlpt.2025.101064

Nouran Hamza , Wael Hafez , Sara Adel Abdelkader Saed , Marina Raouf , Nesma Magdi , Sahar Allam , Rahma Sweedy , Dina Alaraby , Marwa Muhammed Abdeljawad , Nouran A. Taha

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引用次数: 0

Abstract

Background

The complexity and burden of hypertension management necessitate innovative strategies to improve care quality and patient outcomes. Our meta-analysis aimed to evaluate the impact of e-health interventions on hypertension patients' quality of life and medication adherence.

Methods

A systematic review and meta-analysis were conducted using medical electronic databases for literature published before June 30, 2023. Studies investigating the efficacy of mobile health applications on the quality of life of hypertension patients were included. We extracted the studies’ characteristics, patient descriptions, and efficacy outcomes of mobile health applications. Quality assessment was done using ROB 2 and ROBINS-I V2. A meta-analysis was conducted using RevMan software.

Results

The intervention significantly decreased the standardized mean difference of the systolic blood pressure (SBP) measures compared to the control (SMD=-0.43; 95 % CI= -0.52, -0.17; p < 0.01). Additionally, it significantly increased the odds of blood pressure control (OR=3.05; 95 %CI=1.42, 6.54; p < 0.01). The heterogeneity was high; therefore, sensitivity and subgroup analyses were conducted: The intervention significantly increased the quality of life score of hypertension patients compared to the control (SMD=0.19; 95 % CI=0.04, 0.33; p = 0.01). It also significantly decreased the SMD of the SBP change from baseline and the diastolic blood pressure change from baseline compared to the control [(SMD=-4.29; 95 % CI= -5.05, -3.52; p < 0.01), (SMD=-2.75; 95 % CI= -4.06, -1.45; p < 0.01), respectively].

Conclusion

Our study demonstrates the efficacy of e-health interventions in promoting hypertension self-management, highlighting their potential as a scalable and accessible tool among the mobile phone-using population.

Public Interest Summary

Hypertension is a serious disease with severe complications if left uncontrolled. Our goal was to collect all available data on using mobile health applications in hypertension patients to facilitate their medication adherence and thus improve their quality of life. Our results show a noticeable enhancement in blood pressure control and increased patients’ quality of life after using these mobile health applications. This synthesized evidence can help patients and their healthcare providers recognize the strong efficacy and promising outcomes of these applications across multiple studies, which can ultimately lead to widespread utilization and more benefits to patients.

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移动健康应用程序对高血压患者生活质量的影响：系统回顾和荟萃分析

背景：高血压管理的复杂性和负担需要创新策略来提高护理质量和患者预后。我们的荟萃分析旨在评估电子健康干预对高血压患者生活质量和药物依从性的影响。方法利用医学电子数据库对2023年6月30日前发表的文献进行系统评价和meta分析。包括调查移动健康应用程序对高血压患者生活质量的疗效的研究。我们提取了这些研究的特征、患者描述和移动医疗应用程序的疗效结果。采用rob2和ROBINS-I V2进行质量评价。采用RevMan软件进行meta分析。结果与对照组相比，干预显著降低了收缩压（SBP）测量的标准化平均差(SMD=-0.43；95% ci = -0.52, -0.17；p & lt;0.01)。此外，它显著增加血压控制的几率(OR=3.05；95% ci =1.42, 6.54；p & lt;0.01)。异质性高；因此，进行敏感性和亚组分析：干预组高血压患者的生活质量评分较对照组显著提高(SMD=0.19；95% ci =0.04, 0.33；P = 0.01)。与对照组相比，它还显著降低了收缩压变化的SMD值和舒张压变化的SMD值[(SMD=-4.29；95% ci = -5.05, -3.52；p & lt;0.01), (SMD = -2.75;95% ci = -4.06, -1.45；p & lt;0.01),分别)。结论：我们的研究证明了电子健康干预在促进高血压自我管理方面的有效性，强调了它们在使用手机的人群中作为一种可扩展和可获得的工具的潜力。高血压是一种严重的疾病，如果不加以控制，会有严重的并发症。我们的目标是收集关于高血压患者使用移动健康应用程序的所有可用数据，以促进他们的药物依从性，从而提高他们的生活质量。我们的研究结果显示，在使用这些移动健康应用程序后，血压控制明显增强，患者的生活质量也有所提高。这些综合证据可以帮助患者及其医疗保健提供者在多个研究中认识到这些应用程序的强大功效和有希望的结果，从而最终导致广泛使用并为患者带来更多益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Health Policy and Technology Medicine-Health Policy

CiteScore

9.20

自引率

3.30%

发文量

审稿时长

88 days

期刊介绍： Health Policy and Technology (HPT), is the official journal of the Fellowship of Postgraduate Medicine (FPM), a cross-disciplinary journal, which focuses on past, present and future health policy and the role of technology in clinical and non-clinical national and international health environments. HPT provides a further excellent way for the FPM to continue to make important national and international contributions to development of policy and practice within medicine and related disciplines. The aim of HPT is to publish relevant, timely and accessible articles and commentaries to support policy-makers, health professionals, health technology providers, patient groups and academia interested in health policy and technology. Topics covered by HPT will include: - Health technology, including drug discovery, diagnostics, medicines, devices, therapeutic delivery and eHealth systems - Cross-national comparisons on health policy using evidence-based approaches - National studies on health policy to determine the outcomes of technology-driven initiatives - Cross-border eHealth including health tourism - The digital divide in mobility, access and affordability of healthcare - Health technology assessment (HTA) methods and tools for evaluating the effectiveness of clinical and non-clinical health technologies - Health and eHealth indicators and benchmarks (measure/metrics) for understanding the adoption and diffusion of health technologies - Health and eHealth models and frameworks to support policy-makers and other stakeholders in decision-making - Stakeholder engagement with health technologies (clinical and patient/citizen buy-in) - Regulation and health economics