{"title":"The impact of repetitive transcranial magnetic stimulation on anxiety and cognitive function in generalized anxiety disorder: a comprehensive review","authors":"Xuan Zhang , Xiaodong Chen , Leijun Li, Xiuhua Wu, Jiaxin Huang, Xin Qin, Qinsheng Chen, Hongyun Zhou, Jiong Tao, Jihui Wang","doi":"10.1016/j.jadr.2025.100945","DOIUrl":null,"url":null,"abstract":"<div><div>Anxiety disorder is one of the major health burdens in the world, and most of the patients have significantly impaired social function, which seriously affects their quality of life. Currently, conventional treatment methods include medication and psychotherapy. However, due to the limitations of these treatments and the lack of response in some patients, finding effective alternative treatment options has become urgent. Repetitive transcranial magnetic stimulation (rTMS), a relatively non-invasive and safe physical therapy, has been increasingly recommended for anxiety disorders in recent years. Nevertheless, the therapeutic effects, optimal stimulation sites, and stimulation parameters remain unclear. This article aims to provide a systematic review of the current state of rTMS treatment for generalized anxiety disorder(GAD), offering new perspectives for identifying more effective and personalised adjunctive options.</div></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"21 ","pages":"Article 100945"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Affective Disorders Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666915325000757","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Psychology","Score":null,"Total":0}
引用次数: 0
Abstract
Anxiety disorder is one of the major health burdens in the world, and most of the patients have significantly impaired social function, which seriously affects their quality of life. Currently, conventional treatment methods include medication and psychotherapy. However, due to the limitations of these treatments and the lack of response in some patients, finding effective alternative treatment options has become urgent. Repetitive transcranial magnetic stimulation (rTMS), a relatively non-invasive and safe physical therapy, has been increasingly recommended for anxiety disorders in recent years. Nevertheless, the therapeutic effects, optimal stimulation sites, and stimulation parameters remain unclear. This article aims to provide a systematic review of the current state of rTMS treatment for generalized anxiety disorder(GAD), offering new perspectives for identifying more effective and personalised adjunctive options.