Facilitators and barriers to the implementation of Community-Based Medication Adherence Support for Aging Individuals with HIV and Hypertension in western Kenya.

Jepchirchir Kiplagat, Violet Naanyu, Ruth Nehema, Henry Zakumumpa, Kara Wools-Kaloustian
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Abstract

Background The advent of antiretroviral therapy (ART) remarkably improved the longevity and quality of life of people living with HIV (PLWH). However, as PLWH age, they often experience comorbidities, necessitating multiple medications, resulting in increased medication adherence challenges. Patient-tailored community-based medication adherence programs can improve adherence in this population. We explored facilitators of and barriers to the implementation of community health volunteer (CHV)-led medication adherence (CBA) support programs for older people living with HIV (OALWH). Methods This qualitative study involved 166 purposefully sampled participants. In-depth interviews (IDIs) were held with 27 healthcare providers (HCPs), 28 CHVs, and 25 older adults' caregivers. Six focus group discussions (FGDs) were held with 86 OALWH affiliated with three health facilities in western Kenya. The IDIs and FGDs covered topics on perceived barriers and facilitators to having a CHV visit OALWH's home to offer medication adherence support. The data were analyzed thematically and organized using the Consolidated Framework for Implementation Research (CFIR). Results The findings revealed various factors that could influence the implementation of a CBA intervention for OALWH and hypertension. Facilitators included the relative advantage and adaptability of the intervention, the enhanced collaboration between facility and community care providers, and the potential to promote patient-centered care. However, participants voiced several factors that may impede the intervention, such as the complexity of the intervention, increased workload and costs for CHVs, limited knowledge of hypertension management, unmet patient needs, and limited health financing for NCD medications. Fears of decreased cognitive ability, low cardiovascular risk perception, and medication side effects among OALWH were perceived to pose challenges. Furthermore, trust and empathy between CHVs and patients were identified as critical personal attributes that foster patient empowerment. Conclusion This study identified barriers, highlighting the complexities of tailoring community support services to the needs of OALWH. The findings underscore the necessity for a holistic, multidimensional approach to addressing medication adherence by providing OALWH with the requisite hypertension management messaging, revisiting health system barriers (NCD care financing), and facilitating CHVs with knowledge, skills, and remuneration to enable them to efficiently support CBA intervention.

在肯尼亚西部,对艾滋病毒和高血压老年人实施基于社区的药物依从性支持的促进因素和障碍。
抗逆转录病毒疗法(ART)的出现显著提高了艾滋病毒感染者(PLWH)的寿命和生活质量。然而,随着PLWH年龄的增长,他们经常会出现合并症,需要多种药物治疗,从而增加了药物依从性的挑战。患者定制的基于社区的药物依从性项目可以提高这一人群的依从性。我们探讨了社区卫生志愿者(CHV)主导的老年艾滋病毒感染者服药依从性(CBA)支持项目实施的促进因素和障碍。方法对166名被试进行定性研究。对27名医疗保健提供者(HCPs)、28名chv和25名老年人护理人员进行了深度访谈(IDIs)。与隶属于肯尼亚西部三家卫生机构的86个职业妇女健康组织举行了六次焦点小组讨论。idi和fgd涵盖了让CHV访问OALWH家中提供药物依从性支持的感知障碍和促进因素。使用实施研究统一框架(CFIR)对数据进行主题分析和组织。结果研究结果揭示了多种因素可能影响CBA干预OALWH和高血压的实施。促进因素包括干预措施的相对优势和适应性,加强设施和社区护理提供者之间的合作,以及促进以患者为中心的护理的潜力。然而,与会者提出了一些可能阻碍干预的因素,如干预的复杂性、chv的工作量和成本增加、高血压管理知识有限、患者需求未得到满足以及非传染性疾病药物的卫生资金有限。OALWH对认知能力下降、心血管风险认知低和药物副作用的恐惧被认为是构成挑战的因素。此外,chv和患者之间的信任和共情被认为是促进患者授权的关键个人属性。本研究确定了障碍,强调了根据OALWH需求定制社区支持服务的复杂性。研究结果强调了采用一种整体的、多维的方法来解决药物依从性问题的必要性,通过向OALWH提供必要的高血压管理信息,重新审视卫生系统障碍(非传染性疾病护理融资),并向chv提供知识、技能和报酬,使他们能够有效地支持CBA干预。
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