Prevalence and determinants of medication adherence in Moroccan patients with type 2 diabetes: a multicenter cross-sectional study.

IF 2.1 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Osong Public Health and Research Perspectives Pub Date : 2025-07-09 DOI:10.24171/j.phrp.2025.0014

Maryem Arraji, Nadia Al Wachami, Younes Iderdar, Fatima Zahra Bouchachi, Karima Boumendil, Mohamed Chahboune

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Abstract

Objectives: This study was performed to evaluate the prevalence of medication adherence and its determinants among Moroccan patients with type 2 diabetes mellitus.

Methods: A multicenter cross-sectional survey was conducted from February to June 2024, involving 584 patients from the Casablanca-Settat and Rabat-Sale-Kenitra regions of Morocco. Medication adherence was assessed using the general medication adherence scale. Associations between independent variables and adherence were analyzed using chi-square tests and multivariate logistic regression.

Results: Medication adherence was observed in 96.2% of participants. Multivariate analysis revealed significantly lower medication adherence among patients using 2 or more oral antidiabetic drugs (adjusted odds ratio [aOR], 0.026; 95% confidence interval [CI], 0.001-0.642; p=0.026) and those with a diabetes duration of 11 to 15 years (aOR, 0.037; 95% CI, 0.001-0.956; p=0.047).

Conclusion: Despite a high overall adherence rate, patients on dual or polytherapy and those with longer disease duration exhibited lower adherence in multivariate analysis. Targeted interventions are needed to improve adherence in these high-risk groups.

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摩洛哥2型糖尿病患者药物依从性的患病率和决定因素：一项多中心横断面研究

目的：本研究旨在评估摩洛哥2型糖尿病患者的药物依从性及其决定因素。方法：于2024年2月至6月进行多中心横断面调查，涉及来自摩洛哥卡萨布兰卡-塞塔特和拉巴特-萨勒-肯尼特拉地区的584例患者。药物依从性采用一般药物依从性量表进行评估。使用卡方检验和多元逻辑回归分析自变量与依从性之间的关系。结果：96.2%的受试者有服药依从性。多因素分析显示，使用2种及以上口服降糖药的患者药物依从性显著降低(调整优势比[aOR]， 0.026；95%置信区间[CI]， 0.001-0.642；p=0.026)和糖尿病病程为11 ~ 15年的患者(aOR, 0.037；95% ci, 0.001-0.956；p = 0.047)。结论：在多变量分析中，尽管总体依从率较高，但接受双重或多重治疗的患者以及病程较长的患者的依从性较低。需要有针对性的干预措施来提高这些高危人群的依从性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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