{"title":"Innovations and Emerging Therapies in Atopic Dermatitis Part 2.","authors":"Robyn Okereke, Eric Simpson","doi":"10.1007/s40521-025-00389-w","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>The purpose of this review is to discuss the novel aspects of topical therapies used for the treatment of AD. We also discuss the lapses observed when comparing topical therapies. After the innovations regarding systemic therapies in AD were highlighted in a first review (part 1), this second component (part 2) will perceive the advances in topical therapies for AD.</p><p><strong>Recent findings: </strong>Recent history has realized a prompt evolution in the options for topical therapy in AD. Novel, molecularly targeted topical therapies appear to address the drawbacks of traditional topical medicines.</p><p><strong>Summary: </strong>The transformation towards targeted AD therapies is associated with increased efficacy and safety profiles, as well as patient compliance. We also evaluate available real-world and long-term data. Future studies should focus on optimizing topical therapies by increasing the duration of available long-term data.</p>","PeriodicalId":36209,"journal":{"name":"Current Treatment Options in Allergy","volume":"12 ","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233182/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Treatment Options in Allergy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s40521-025-00389-w","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/3 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ALLERGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose of review: The purpose of this review is to discuss the novel aspects of topical therapies used for the treatment of AD. We also discuss the lapses observed when comparing topical therapies. After the innovations regarding systemic therapies in AD were highlighted in a first review (part 1), this second component (part 2) will perceive the advances in topical therapies for AD.
Recent findings: Recent history has realized a prompt evolution in the options for topical therapy in AD. Novel, molecularly targeted topical therapies appear to address the drawbacks of traditional topical medicines.
Summary: The transformation towards targeted AD therapies is associated with increased efficacy and safety profiles, as well as patient compliance. We also evaluate available real-world and long-term data. Future studies should focus on optimizing topical therapies by increasing the duration of available long-term data.
期刊介绍：
Current Treatment Options in Allergy will focus on the latest advances in the treatment of allergic disorders. Designed for physicians, this journal offers expert reviews on the management of skin allergies, venom allergies, rhinitis, asthma, food allergies, drug allergies, atopic dermatitis, allergy prevention, and anaphylaxis.Articles cover a range of established and emerging treatment options. We accomplish this by having experts present the latest research, assess the efficacy of available treatment options, and discuss special considerations. We ensure that the journal content includes current, emerging research and suggest articles of special interest.
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