Beyond skin deep: the unseen burden of hidradenitis suppurativa on sleep and quality of life.

IF 1.3 4区医学 Q3 OPHTHALMOLOGY

Cutaneous and Ocular Toxicology Pub Date : 2025-09-01 Epub Date: 2025-07-09 DOI:10.1080/15569527.2025.2526607

Ezgi Sanlı, Bilal Sula, Mustafa Esen

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引用次数: 0

Abstract

Objectives: Hidradenitis suppurativa (HS) causes pain, discharge, odor, and scarring, potentially worsening sleep quality and psychological health. This study evaluated sleep, mood, and quality of life in HS patients compared to healthy controls, considering disease severity. We hypothesized that increased HS severity significantly impairs these outcomes.

Methods: This case-control study involved 55 HS patients from a university hospital and 55 healthy controls. Participants completed the Dermatology Life Quality Index (DLQI), Pittsburgh Sleep Quality Index (PSQI), and Hospital Anxiety and Depression Scale (HADS). HS severity was assessed using the Hurley staging system, and pain was measured with the Visual Analog Scale (VAS).

Results: HS patients had significantly higher anxiety, depression, DLQI, and PSQI scores than controls (p < 0.001). Depression scores correlated with Hurley stage (p = 0.041), but anxiety, DLQI, and PSQI scores did not (p > 0.05). VAS pain scores over the past week correlated with anxiety (p = 0.005), depression (p = 0.020), and DLQI scores (p < 0.001). DLQI scores positively correlated with depression, anxiety, and PSQI scores (p < 0.001, p < 0.001, p = 0.004, respectively). Depression scores correlated with anxiety and PSQI scores (p < 0.001 for both). Anxiety and PSQI scores also showed a positive correlation (p < 0.001).

Conclusion: HS is associated with poorer mood, sleep quality, and quality of life compared to healthy controls.

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超越皮肤深层：化脓性汗腺炎对睡眠和生活质量的无形负担。

目的：化脓性汗腺炎（HS）引起疼痛、分泌物、气味和疤痕，潜在地恶化睡眠质量和心理健康。考虑到疾病的严重程度，本研究评估了HS患者与健康对照者的睡眠、情绪和生活质量。我们假设HS严重程度的增加会显著损害这些结果。方法：本病例-对照研究纳入某大学医院55例HS患者和55名健康对照者。参与者完成皮肤病生活质量指数（DLQI）、匹兹堡睡眠质量指数（PSQI）和医院焦虑抑郁量表（HADS）。采用Hurley分期系统评估HS严重程度，采用视觉模拟评分（VAS）测量疼痛。结果：HS患者焦虑、抑郁、DLQI、PSQI评分明显高于对照组（p < 0.001）。抑郁评分与Hurley分期相关（p = 0.041），而焦虑、DLQI、PSQI评分无相关性（p < 0.05）。过去一周的VAS疼痛评分与焦虑（p = 0.005）、抑郁（p = 0.020）和DLQI评分（p < 0.001）相关。DLQI评分与抑郁、焦虑、PSQI评分呈正相关（p < 0.001, p < 0.001, p = 0.004）。抑郁评分与焦虑和PSQI评分相关（两者均p < 0.001）。焦虑与PSQI评分也呈正相关（p < 0.001）。结论：与健康对照组相比，HS与较差的情绪、睡眠质量和生活质量有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cutaneous and Ocular Toxicology 医学-毒理学

CiteScore

3.30

自引率

6.20%

发文量

审稿时长

1 months

期刊介绍： Cutaneous and Ocular Toxicology is an international, peer-reviewed journal that covers all types of harm to cutaneous and ocular systems. Areas of particular interest include pharmaceutical and medical products; consumer, personal care, and household products; and issues in environmental and occupational exposures. In addition to original research papers, reviews and short communications are invited, as well as concise, relevant, and critical reviews of topics of contemporary significance.