Childhood Vaccinations in Children With Food or Vaccination-Related Allergic Reactions: A Single-Center Experience.

IF 1 4区医学 Q3 PEDIATRICS

Clinical Pediatrics Pub Date : 2025-07-08 DOI:10.1177/00099228251354850

Tülay Tuğçe Kutsal Gültekin, Kezban İpek Demir, Zeynep Şengül Emeksiz, Aysun Kara Uzun, Emine Dibek Mısırlıoğlu

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引用次数: 0

Abstract

Background: Children with allergic reactions are mostly referred to tertiary centers for vaccination, but confirmed vaccination-triggered allergic reactions are uncommon. In this study, childhood vaccination-triggered allergic reactions in children with food and vaccination-related allergies are evaluated.

Methodology: Retrospective analysis of 923 doses of vaccine administered in our clinic due to food or vaccine-triggered allergic reactions were conducted.

Results: 868 vaccines were measles-mumps-rubella (MMR) vaccine, 20 were measles vaccine containing alpha-lactalbumin and 35 were other childhood vaccines. A total of 576 of MMR vaccines contained alpha-lactalbumin and 292 did not. Vaccinations were administered without any reactions in 98.9% of patients with previous food allergies. One of the reactions was anaphylaxis. About 55 patients were referred because of previous vaccination-related allergic reactions, and 94.5% of them were vaccinated without any reactions. Mild reactions were encountered in 3 (5.5%) patients. No anaphylaxis was observed.

Conclusion: Patients with a history of food or vaccination allergies have a low rate of allergic reactions in childhood vaccinations.

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有食物或疫苗相关过敏反应的儿童的儿童疫苗接种：单中心经验。

背景：有过敏反应的儿童大多转诊到三级中心接种疫苗，但确诊的疫苗引发的过敏反应并不常见。在这项研究中，儿童疫苗引发的过敏反应与食物和疫苗相关过敏的儿童进行评估。方法：回顾性分析我院923剂因食物或疫苗引起的过敏反应而接种的疫苗。结果：麻疹-腮腺炎-风疹（MMR）疫苗868支，含α -乳清蛋白麻疹疫苗20支，其他儿童疫苗35支。共有576种MMR疫苗含有α -乳清蛋白，292种不含。98.9%以前有食物过敏的患者接种疫苗后没有任何反应。其中一个反应是过敏反应。约55例患者因既往疫苗相关过敏反应而转诊，其中94.5%的患者接种疫苗后无任何反应。轻度反应3例（5.5%）。未观察到过敏反应。结论：有食物或疫苗过敏史的患者在儿童期接种疫苗时过敏反应发生率低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Pediatrics 医学-小儿科

CiteScore

2.10

自引率

6.20%

发文量

189

审稿时长

3-8 weeks

期刊介绍： Clinical Pediatrics (CLP) a peer-reviewed monthly journal, is a must read for the busy pediatrician. CLP contains state-of-the-art, accurate, concise and down-to earth information on practical, everyday child care topics whether they are clinical, scientific, behavioral, educational, or ethical.