Modern Strategies in Wound Healing: The Rise of Bacterial Cellulose Dressings

Abstract

Advancements in wound care have necessitated the development of innovative dressings that address the limitations of traditional options while enhancing the healing process. Bacterial cellulose (BC) stands out due to its exceptional properties, including high water retention, biocompatibility, mechanical strength, and modification adaptability. This review critically compares BC-based wound dressings with traditional and next-generation alternatives, highlighting their unique advantages and potential as ideal wound coverings. BC's ability to maintain a moist environment, promote tissue regeneration, and minimize secondary injuries during dressing changes positions it as a superior option in wound care. BC's nanoporous structure also supports its functionalization with bioactive agents, antimicrobial compounds, and advanced fabrication techniques such as 3D printing and electrospinning. These modifications allow for tailored solutions that meet specific wound care requirements. Despite high production costs and the absence of intrinsic antimicrobial properties, BC surpasses many traditional dressings by addressing key areas such as moisture retention, biocompatibility, and ease of use. This study emphasizes BC's potential to transform wound care by combining its inherent properties with innovative modifications. BC-based dressings offer promising avenues for developing more effective, tailored, and sustainable wound management strategies by bridging the gap between traditional and next-generation solutions.