[Adverse drug reaction in a patient with autoimmune disease: Case report].

María Camila Castanier-Dávila, Paúl Leonardo Wilches-Coronel
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Abstract

Background: Adverse drug reactions are harmful and unintentional events related to medication use. Stevens-Johnson Syndrome is a serious adverse drug reaction that can progress to toxic epidermal necrolysis and is related to certain medications. It can even be triggered by infections and genetic factors.

Case report: A 62-year-old female patient with high blood pressure developed severe skin lesions after self-medicating with paracetamol and ibuprofen. She recovered favorably after several treatments and admissions to the Intensive Care Unit.

Conclusion: It is important to promptly identify the triggering factors of adverse drug reactions in order to intervene appropriately. The administration of corticosteroids and IV immunoglobulin is still under discussion. Immediate attention is required to improve clinical outcomes and comprehensive treatment, thus optimizing the outcome.

自身免疫性疾病患者药物不良反应1例报告
背景:药物不良反应是与药物使用相关的有害和非故意事件。史蒂文斯-约翰逊综合征是一种严重的药物不良反应,可发展为中毒性表皮坏死松解,与某些药物有关。它甚至可以由感染和遗传因素引发。病例报告:一名62岁的女性高血压患者在服用扑热息痛和布洛芬后出现严重的皮肤损伤。经过几次治疗和入住重症监护室后,她恢复得很好。结论:及时识别药物不良反应的触发因素,进行适当干预是十分重要的。皮质类固醇和静脉注射免疫球蛋白的使用仍在讨论中。提高临床疗效,综合治疗,优化治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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