Normative study of the Taiwanese version of the Montreal Cognitive Assessment (MoCA) in community-dwelling individuals in Taiwan.

Yu-Hsiang Cheng, Shih-Chieh Lee, Yen-Ching Chen, Jen-Hau Chen, Rwei-Ling Yu, Wei-Ju Lee, Jung-Lung Hsu, Cheng-Sheng Chen, Jong-Ling Fuh
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Abstract

Background: The Montreal Cognitive Assessment (MoCA) may not be appropriately interpreted in Taiwan because of the lack of large-scale normative data. Moreover, examinees' demographic characteristics may influence their MoCA scores. However, previous studies have not adequately adjusted for these effects. This study aimed to use regression-based methods to establish demographically adjusted MoCA norms.

Methods: Participants were recruited from six hospitals and neighboring communities from all geographic areas of Taiwan. Multiple regression analyses were conducted to quantify the effects of age, education, and sex on MoCA total and domain scores, resulting in correction equations and adjusted cutoff scores.

Results: A total of 2,310 cognitively healthy participants were included in the analysis. Age and education significantly affected the total and all domain scores. Sex affected naming, language, and abstract thinking domain scores. Correction equations and corresponding cutoffs were proposed for MoCA total and domain scores to support more precise clinical interpretations.

Conclusion: This study provides regression-adjusted norms for the MoCA, improving its accuracy and clinical utility in Taiwan. An adjusted total MoCA score of 23 points is recommended as the cutoff for identifying potential cognitive impairment, with domain-specific cutoffs further supporting individualized interpretation.

台湾版蒙特娄认知评估(MoCA)在台湾社区居民中的规范研究。
背景:由于缺乏大规模的规范资料,蒙特娄认知评估(MoCA)在台湾可能无法正确解读。此外,考生的人口特征可能会影响他们的MoCA分数。然而,以前的研究并没有充分调整这些影响。本研究旨在利用回归方法建立经人口统计调整的MoCA规范。方法:研究对象来自台湾各地理区域的六家医院及邻近社区。通过多元回归分析,量化年龄、教育程度和性别对MoCA总分和领域得分的影响,得出修正方程和调整的截止分数。结果:共有2,310名认知健康的参与者被纳入分析。年龄和受教育程度显著影响总分和各领域得分。性别影响命名、语言和抽象思维领域得分。提出了MoCA总分和域分数的修正方程和相应的截止点,以支持更精确的临床解释。结论:本研究提供了经回归校正的MoCA标准,提高了MoCA的准确性和临床应用价值。调整后的MoCA总分为23分,建议作为识别潜在认知障碍的分界点,特定领域的分界点进一步支持个性化解释。
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