A Case of Colon Leiomyosarcoma Arising from the Muscularis Mucosae: A Case Report and Literature Review.

IF 0.7 Q4 SURGERY

Surgical Case Reports Pub Date : 2025-01-01 Epub Date: 2025-07-02 DOI:10.70352/scrj.cr.25-0146

Yuta Kasagi, Masahiko Sugiyama, Rena Yokomizo, Munehide Terashi, Taichiro Nagai, Naomichi Koga, Ayako Iwanaga, Yasue Kimura, Yutaka Koga, Kenichi Taguchi, Masaru Morita

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Abstract

Introduction: Colon leiomyosarcoma (CLMS) is an extremely rare neoplasm and the information regarding its clinical characteristics and specific treatment was still unclear.

Case presentation: A 73-year-old female who had been diagnosed with transverse CLMS underwent laparoscopic surgery. The resected specimen showed that the tumor contained proliferation of spindle-shaped cells and arranged in fascicular pattern, which was immunohistochemically positive for smooth muscle actin and desmin. Moreover, the tumor bottom was not continuous with the muscularis propria and had a clear border in the submucosa layer. According to these findings, we finally diagnosed it as primary CLMS arising from the muscularis mucosa (MM). No recurrence was noted 24 months after surgery.

Conclusions: This literature demonstrates CLMS arising from MM and suggests that its pathological diagnosis is associated with disease prognosis.

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结肠平滑肌肉瘤发生于粘膜肌层1例报告并文献复习。

结肠平滑肌肉瘤（Colon平滑肌肉瘤，CLMS）是一种极为罕见的肿瘤，其临床特征和具体治疗方法尚不清楚。病例介绍：一位73岁女性，被诊断为横贯性CLMS，接受腹腔镜手术。切除标本显示肿瘤呈梭形细胞增生，呈束状排列，平滑肌肌动蛋白和desmin免疫组化阳性。肿瘤底部与固有肌层不连续，粘膜下层边界清晰。根据这些发现，我们最终诊断为原发性CLMS起源于粘膜肌层（MM）。术后24个月无复发。结论：本文献证实CLMS起源于MM，其病理诊断与疾病预后相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Surgical Case Reports SURGERY-

自引率

0.00%

发文量

218

审稿时长

13 weeks