The need for an organoid manufacturing, preservation, and distribution center.

IF 5.4 2区医学 Q1 CELL & TISSUE ENGINEERING

Stem Cells Translational Medicine Pub Date : 2025-06-25 DOI:10.1093/stcltm/szaf031

Anthony Atala, John C Bischof, Christopher S Chen, John P Fisher, David L Hermanson, Charles L Howe, Walter C Low, Zhen Ma, David H McKenna, Sean P Palecek, Johnna S Temenoff, Brenda M Ogle

引用次数: 0

Abstract

Organoids, which are tiny, lab-grown 3D structures that mimic some organizational and functional properties of human organs, are slowly transforming the face of systems and developmental biology, biomedical research, pharmaceutical testing, environmental toxin testing, and healthcare. Significant investments are essential for the mass production, preservation, and distribution of organoids, with the aim to accelerate innovation and progress across multiple fields-much like the investments made in cell and biologics manufacturing over the past 2 decades.

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对类器官制造、保存和配送中心的需求。

类器官是一种微小的、实验室培养的3D结构，模仿了人类器官的一些组织和功能特性，正在慢慢改变系统和发育生物学、生物医学研究、药物测试、环境毒素测试和医疗保健的面貌。大量投资对于类器官的大规模生产、保存和分销至关重要，其目的是加速多个领域的创新和进步——就像过去20年对细胞和生物制剂制造的投资一样。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Stem Cells Translational Medicine CELL & TISSUE ENGINEERING-

CiteScore

12.90

自引率

3.30%

发文量

140

审稿时长

6-12 weeks

期刊介绍： STEM CELLS Translational Medicine is a monthly, peer-reviewed, largely online, open access journal. STEM CELLS Translational Medicine works to advance the utilization of cells for clinical therapy. By bridging stem cell molecular and biological research and helping speed translations of emerging lab discoveries into clinical trials, STEM CELLS Translational Medicine will help move applications of these critical investigations closer to accepted best patient practices and ultimately improve outcomes. The journal encourages original research articles and concise reviews describing laboratory investigations of stem cells, including their characterization and manipulation, and the translation of their clinical aspects of from the bench to patient care. STEM CELLS Translational Medicine covers all aspects of translational cell studies, including bench research, first-in-human case studies, and relevant clinical trials.