Visual Acuity and Quality of Life Results in a Randomized Trial of Topography-Guided LASIK With GIS Software Versus Wavefront-Optimized LASIK.

IF 2.9 3区医学 Q1 OPHTHALMOLOGY

Journal of refractive surgery Pub Date : 2025-07-01 DOI:10.3928/1081597X-20250509-01

Elise V H Meide, Tanner J Ferguson, John P Berdahl, Vance M Thompson, Daniel C Terveen

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引用次数: 0

Abstract

Purpose: To compare visual and refractive outcomes and patient-reported visual quality of life between topography-guided laser in situ keratomileusis with novel geographic imaging system (TG-GIS LASIK)-based software versus wavefront-optimized (WFO) LASIK.

Methods: This was a prospective, multi-site, randomized, clinical trial. Patients with bilateral myopic LASIK were randomized 1:1 to undergo bilateral TG-GIS LASIK or WFO LASIK using the Wavelight EX500 laser (Alcon Laboratories, Inc). The main outcome measure was the percentage of patients with monocular uncorrected distance visual acuity (UDVA) of 20/16 or better at 3 months. The Patient Reported Outcome With LASIK questionnaire was administered preoperatively and 3 months postoperatively.

Results: One hundred seventeen patients (234 eyes) were enrolled. For monocular UDVA, 29% in the WFO LASIK group achieved 20/12.5 and 74.6% achieved 20/16 or better versus 18% (P = .05) and 67% of the TG-GIS LASIK group, respectively (P = .29). For mean refractive spherical equivalent, the percentage of eyes within ±0.50 diopters (D) of plano was 97% in the WFO LASIK group and 91% in the TG-GIS LASIK group (P = .09). The WFO LASIK group had 14% of eyes gain two lines of corrected distance visual acuity versus 7% (P = .09) in the TG-GIS LASIK group. Overall satisfaction was similar between groups (93.66, 91.77, P = .18) but there was increased satisfaction as it relates to magnitude of starbursts in the TG-GIS LASIK group (85.74 TG-GIS LASIK group, 81.62 WFO LASIK group, P = .03).

Conclusions: WFO LASIK trended toward higher rates of 20/12.5 UDVA but achieved similar rates of 20/16 UDVA and slightly superior refractive outcomes compared to TG-GIS LASIK. Overall, visual and refractive outcomes were favorable in both groups. Both groups had high patient satisfaction. [J Refract Surg. 2025;41(7):e625-e634.].

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地理信息系统辅助的地形引导LASIK与波前优化LASIK的视力和生活质量的随机对照研究

目的：比较基于新型地理成像系统（TG-GIS LASIK）软件的地形引导激光原位角膜磨晶状体手术与波前优化（WFO） LASIK手术的视力和屈光结果以及患者报告的视觉生活质量。方法：这是一项前瞻性、多地点、随机、临床试验。双侧近视LASIK患者按1:1随机分为两组，分别使用waveight EX500激光器（Alcon Laboratories, Inc）接受双侧TG-GIS LASIK或WFO LASIK。主要结局指标是3个月时单眼未矫正距离视力（UDVA）为20/16或更好的患者百分比。术前和术后3个月进行LASIK患者报告结果问卷调查。结果：入组117例（234只眼）。对于单眼UDVA， WFO LASIK组29%达到20/12.5,74.6%达到20/16或更好，而TG-GIS LASIK组分别为18% （P = 0.05）和67% （P = 0.29）。对于平均屈光球等效，WFO LASIK组在±0.50屈光(D)范围内的眼睛百分比为97%，TG-GIS LASIK组为91% （P = 0.09）。WFO LASIK组有14%的眼睛获得两线矫正距离视力，而TG-GIS LASIK组有7% （P = 0.09）。两组患者的总体满意度相似（93.66,91.77,P = 0.18），但TG-GIS LASIK组患者对星暴星等的满意度有所提高（TG-GIS LASIK组85.74，WFO LASIK组81.62,P = 0.03）。结论：与TG-GIS LASIK相比，WFO LASIK倾向于更高的20/12.5 UDVA率，但达到相似的20/16 UDVA率，屈光效果略好。总的来说，两组的视力和屈光结果都很好。两组患者满意度均较高。[J].中华眼科杂志，2015;41(7):625- 634。

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来源期刊

$Journal of refractive surgery$

Journal of refractive surgery 医学-外科

CiteScore

5.10

自引率

12.50%

发文量

160

审稿时长

4-8 weeks

期刊介绍： The Journal of Refractive Surgery, the official journal of the International Society of Refractive Surgery, a partner of the American Academy of Ophthalmology, has been a monthly peer-reviewed forum for original research, review, and evaluation of refractive and lens-based surgical procedures for more than 30 years. Practical, clinically valuable articles provide readers with the most up-to-date information regarding advances in the field of refractive surgery. Begin to explore the Journal and all of its great benefits such as: • Columns including “Translational Science,” “Surgical Techniques,” and “Biomechanics” • Supplemental videos and materials available for many articles • Access to current articles, as well as several years of archived content • Articles posted online just 2 months after acceptance.