Hidradenitis Suppurativa Prevalence in Indonesia: A Cross-Sectional Multicenter Study and Validation of a Screening Questionnaire.

IF 2.7 3区医学 Q2 DERMATOLOGY

Dermatology Pub Date : 2025-07-07 DOI:10.1159/000539705

Shinta Trilaksmi Dewi, Nyoman Suryawati, Niken Indrastuti, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec, Nisha S Chandran, Miranti Pangastuti, Aryani Adji, Gardenia Akhyar, Nopriyati Nopriyati, Cut Putri Hazlianda, Sri Awalia Febriana

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引用次数: 0

Abstract

Introduction: Studies on the prevalence of hidradenitis suppurative (HS) in Southeast Asia are scarce, and no studies have been conducted in Indonesia. This study aimed to calculate the prevalence of HS in Indonesia and validate this questionnaire in our population as part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative.

Methods: This multicenter cross-sectional study was conducted at 7 teaching hospitals in western and central Indonesia from December 2022 to June 2023. A total of 3,237 healthy adults accompanying patients in the outpatient clinics consented to participate. Physicians or nurses delivered the validated screening questionnaire, and photos of the axilla and groin were taken from screen-positive individuals and 10% of the screen-negative individuals. The dermatologist examined the clinical photos to confirm the diagnosis of HS.

Results: The prevalence of HS in our study population was 0.43% (14/3,237; with 95% confidence interval [CI]: 0.26%-0.72%), and there was no significant difference in gender, age, body mass index (BMI), and smoking habit between the HS and non-HS groups. In the HS group, males and females were equally affected, with the median age being 29 years with interquartile range (IQR: 24.8-38.5), median BMI of 23.0 (IQR: 21.1-26.4), and 28.6% being smokers. The screening questionnaire showed a sensitivity of 0.43 (6/14; 95% CI: 0.18-0.17), specificity of 0.94 (362/386; 95% CI: 0.91-0.96), positive predictive value of 0.20 (6/30; 95% CI: 0.08-0.39), and negative predictive value of 0.98 (362/370; 95% CI: 0.96-0.99).

Conclusion: The prevalence of HS in Indonesia is 0.43%, slightly lower than those reported in other Southeast Asian countries. Age, gender, BMI, and smoking habits were not risk factors for HS in our population. The questionnaire is moderately accurate for screening HS but remains valuable in detecting around 50% of undiagnosed cases.

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印度尼西亚化脓性汗腺炎的流行：一项横断面多中心研究和筛选问卷的验证。

导读：关于东南亚地区化脓性汗腺炎（HS）流行情况的研究很少，印度尼西亚尚未开展相关研究。本研究旨在计算HS在印度尼西亚的患病率，并作为全球化脓性汗腺炎地图集（GHiSA）计划的一部分，在我们的人群中验证该问卷。方法：于2022年12月至2023年6月在印度尼西亚西部和中部的7所教学医院进行多中心横断面研究。共有3,237名在门诊陪同患者的健康成年人同意参与研究。医生或护士发放有效的筛查问卷，并从筛查阳性的个体和10%的筛查阴性的个体中拍摄腋窝和腹股沟的照片。皮肤科医生检查了临床照片以确认HS的诊断。结果：研究人群HS患病率为0.43% (14/3,237；95%可信区间[CI]: 0.26% ~ 0.72%)， HS组与非HS组在性别、年龄、体重指数（BMI）、吸烟习惯等方面均无显著差异。在HS组中，男性和女性受到的影响相同，年龄中位数为29岁，四分位数范围（IQR: 24.8-38.5）， BMI中位数为23.0 (IQR: 21.1-26.4)， 28.6%为吸烟者。筛选问卷的敏感性为0.43 (6/14；95% CI: 0.18-0.17)，特异性0.94 (362/386；95% CI: 0.91-0.96)，阳性预测值为0.20 (6/30；95% CI: 0.08-0.39)，阴性预测值为0.98 (362/370；95% ci: 0.96-0.99)。结论：印度尼西亚HS患病率为0.43%，略低于其他东南亚国家。在我们的人群中，年龄、性别、BMI和吸烟习惯不是HS的危险因素。该问卷对HS筛查具有中等准确性，但在发现约50%未确诊病例方面仍有价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dermatology 医学-皮肤病学

CiteScore

6.40

自引率

2.90%

发文量

审稿时长

1 months

期刊介绍： Published since 1893, ''Dermatology'' provides a worldwide survey of clinical and investigative dermatology. Original papers report clinical and laboratory findings. In order to inform readers of the implications of recent research, editorials and reviews prepared by invited, internationally recognized scientists are regularly featured. In addition to original papers, the journal publishes rapid communications, short communications, and letters to ''Dermatology''. ''Dermatology'' answers the complete information needs of practitioners concerned with progress in research related to skin, clinical dermatology and therapy. The journal enjoys a high scientific reputation with a continually increasing impact factor and an equally high circulation.