A Case Report of Necrolytic Migratory Erythema Associated with Glucagonoma.

IF 1.9 4区 医学 Q3 DERMATOLOGY
Clinical, Cosmetic and Investigational Dermatology Pub Date : 2025-07-03 eCollection Date: 2025-01-01 DOI:10.2147/CCID.S508305
Di Xia, Zhouliang Liu, Jiamin Li, Jingjing Liu, Yongbin Qu
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引用次数: 0

Abstract

Necrolytic migratory erythema(NME) is a rare dermatitis usually associated with pancreatic neuroendocrine tumor as a manifestation of glucogonoma syndrome. Over the past five years, NME has been scarcely reported in the literature, with only 8 cases globally. The age range of affected individuals spans from 28 to 62 years, with a mean onset age of 49.4 years. This report presents a 41-year-old male diagnosed with NME secondary to glucagonoma, highlighting the critical need for heightened clinical vigilance in younger NME patients. And NME can mimic other dermatological conditions, leading to potential misdiagnosis and late tumor identification. This case highlights the typical clinical features, aiming to enhance the diagnostic efficiency and accuracy for NME.

坏死性迁移性红斑伴胰高血糖素升高1例。
坏死性迁移性红斑(NME)是一种罕见的皮炎,通常与胰神经内分泌肿瘤相关,为糖原瘤综合征的表现。在过去的五年中,NME在文献中几乎没有报道,全球只有8例。受影响个体的年龄范围为28 ~ 62岁,平均发病年龄为49.4岁。本报告报告了一名41岁男性诊断为继发于胰高血糖素瘤的NME,强调了对年轻NME患者提高临床警惕性的迫切需要。NME可以模仿其他皮肤病,导致潜在的误诊和晚期肿瘤鉴定。本病例突出了典型的临床特征,旨在提高NME的诊断效率和准确性。
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来源期刊
CiteScore
2.80
自引率
4.30%
发文量
353
审稿时长
16 weeks
期刊介绍: Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.
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