Diana Paleacu Kertesz, Liat Mor, Ann Dekalo, Eran Weiner, Yossi Mizrachi, Anna Milstein, Giulia Barda
{"title":"Anxiety, depression and cognitive characteristics of women with twin versus singleton pregnancy.","authors":"Diana Paleacu Kertesz, Liat Mor, Ann Dekalo, Eran Weiner, Yossi Mizrachi, Anna Milstein, Giulia Barda","doi":"10.1007/s00737-025-01611-z","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Maternal anxiety, depression, and cognitive changes during pregnancy are recognized as significant public health issues. While previous research has primarily focused on singleton pregnancies, little is known about how twin pregnancies impact maternal mental health and cognitive function. This prospective study aimed to compare anxiety, depression, and cognitive function between women with twin and singleton pregnancies.</p><p><strong>Methods: </strong>A total of 160 pregnant women were recruited, including 104 with singleton and 56 with twin pregnancies. Anxiety was assessed using the State-Trait Anxiety Inventory Scale (STAI-S), depression using the Edinburgh Postnatal Depression Scale (EPDS), and cognitive function using the Montreal Cognitive Assessment (MOCA) test.</p><p><strong>Results: </strong>Women with twin pregnancies had significantly higher anxiety levels and a higher rate of severe anxiety, with over 50% scoring in the severe anxiety range. Their mean cognitive function scores were significantly lower compared to women with singleton pregnancies. However, depression scores were similar between the two groups. These differences in anxiety and cognitive function remained significant after adjusting for maternal age, BMI, use of psychiatric medications, education level, nulliparity, pregnancy complications, and multifetal gestation.</p><p><strong>Conclusions: </strong>Women with twin pregnancies experience greater psychological burden and cognitive decline compared to those with singleton pregnancies. Further research is necessary to explore the long-term effects of these outcomes and to develop interventions aimed at improving mental health and cognitive function in this population.</p>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":" ","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Women's Mental Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00737-025-01611-z","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: Maternal anxiety, depression, and cognitive changes during pregnancy are recognized as significant public health issues. While previous research has primarily focused on singleton pregnancies, little is known about how twin pregnancies impact maternal mental health and cognitive function. This prospective study aimed to compare anxiety, depression, and cognitive function between women with twin and singleton pregnancies.
Methods: A total of 160 pregnant women were recruited, including 104 with singleton and 56 with twin pregnancies. Anxiety was assessed using the State-Trait Anxiety Inventory Scale (STAI-S), depression using the Edinburgh Postnatal Depression Scale (EPDS), and cognitive function using the Montreal Cognitive Assessment (MOCA) test.
Results: Women with twin pregnancies had significantly higher anxiety levels and a higher rate of severe anxiety, with over 50% scoring in the severe anxiety range. Their mean cognitive function scores were significantly lower compared to women with singleton pregnancies. However, depression scores were similar between the two groups. These differences in anxiety and cognitive function remained significant after adjusting for maternal age, BMI, use of psychiatric medications, education level, nulliparity, pregnancy complications, and multifetal gestation.
Conclusions: Women with twin pregnancies experience greater psychological burden and cognitive decline compared to those with singleton pregnancies. Further research is necessary to explore the long-term effects of these outcomes and to develop interventions aimed at improving mental health and cognitive function in this population.
期刊介绍：
Archives of Women’s Mental Health is the official journal of the International Association for Women''s Mental Health, Marcé Society and the North American Society for Psychosocial Obstetrics and Gynecology (NASPOG). The exchange of knowledge between psychiatrists and obstetrician-gynecologists is one of the major aims of the journal. Its international scope includes psychodynamics, social and biological aspects of all psychiatric and psychosomatic disorders in women. The editors especially welcome interdisciplinary studies, focussing on the interface between psychiatry, psychosomatics, obstetrics and gynecology. Archives of Women’s Mental Health publishes rigorously reviewed research papers, short communications, case reports, review articles, invited editorials, historical perspectives, book reviews, letters to the editor, as well as conference abstracts. Only contributions written in English will be accepted. The journal assists clinicians, teachers and researchers to incorporate knowledge of all aspects of women’s mental health into current and future clinical care and research.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
