Bone Marrow Aspirate Concentrate With Hip Arthroscopy in a Heterogenous Group of Patients May Result in Improved Patient-Reported Outcomes: A Systematic Review.
Michael S Lee, Nicholas J Pettinelli, Jack Gagné, Justin Zhu, Mackenzie Norman, Louise Atadja, Ronak J Mahatme, Scott Fong, Jay Moran, Stephen M Gillinov, Wasif Islam, Nancy Park, Andrew E Jimenez
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引用次数: 0
Abstract
Introduction: There is little literature reporting on the efficacy of bone marrow aspirate concentrate (BMAC) in conjunction with hip arthroscopy.
Purpose: We sought to systematically review the literature on BMAC use following hip arthroscopy, in particular, whether its use results in improved patient-reported outcome measures (PROMs).
Methods: The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were followed when querying PubMed, Cochrane Central Register of Controlled Trials, and Scopus in January 2023. Articles were included if they reported on pre- and postoperative outcomes for patients undergoing hip arthroscopy with concomitant BMAC and were written in English.
Results: Five articles were included in the review. A total of 252 hips undergoing BMAC and hip arthroscopy performed between 2010 and 2020 were evaluated. The average age of patients in the studies ranged between 32.8 and 48.5 years. All studies reported improved postoperative PROM scores compared to preoperative outcome scores after BMAC and hip arthroscopy. Two studies reported survivorship of 100% and 85.7%. All 5 studies conducted a subanalysis between BMAC and hip arthroscopy and a control group. Three studies reported superior outcomes in the BMAC and hip arthroscopy group, while another study reported findings that trended toward favoring the BMAC and hip arthroscopy group but that did not reach statistical significance.
Conclusion: BMAC may improve outcomes in patients undergoing hip arthroscopy. However, due to the small sample size and lack of standardized control groups, the results of this systematic review are inconclusive.
关于骨髓浓缩液(BMAC)联合髋关节镜治疗的疗效的文献报道很少。目的:我们试图系统地回顾髋关节镜术后使用BMAC的文献,特别是使用BMAC是否能改善患者报告的结果测量(PROMs)。方法:在2023年1月查询PubMed、Cochrane Central Register of Controlled Trials和Scopus时,遵循系统评价和meta分析指南的首选报告项目。如果文章报道了髋关节镜下合并BMAC患者的术前和术后结果,并以英文撰写,则纳入。结果:共纳入5篇文章。在2010年至2020年期间,共有252个髋关节接受了BMAC和髋关节镜检查。研究中患者的平均年龄在32.8至48.5岁之间。所有研究都报告了BMAC和髋关节镜手术后术后PROM评分与术前结果评分相比的改善。两项研究报告了100%和85.7%的生存率。所有5项研究都在BMAC和髋关节镜以及对照组之间进行了亚分析。三项研究报告了BMAC和髋关节镜组的优越结果,而另一项研究报告的结果倾向于BMAC和髋关节镜组,但没有达到统计学意义。结论:BMAC可改善髋关节镜患者的预后。然而,由于样本量小且缺乏标准化的对照组,本系统综述的结果尚无定论。
期刊介绍:
The HSS Journal is the Musculoskeletal Journal of Hospital for Special Surgery. The aim of the HSS Journal is to promote cutting edge research, clinical pathways, and state-of-the-art techniques that inform and facilitate the continuing education of the orthopaedic and musculoskeletal communities. HSS Journal publishes articles that offer contributions to the advancement of the knowledge of musculoskeletal diseases and encourages submission of manuscripts from all musculoskeletal disciplines.