Lumbar methicillin-resistant Staphylococcus aureus infection caused by a peripherally inserted central catheter: A case report.

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

World Journal of Clinical Cases Pub Date : 2025-07-06 DOI:10.12998/wjcc.v13.i19.104294

Xiao-Xiao Yuan, Qiong-Qiong Tan, Chen Chen, Qing-Qing He, Yan-Ning Li

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Abstract

Background: Peripherally inserted central catheters (PICCs) are widely used for administering chemotherapy to breast cancer patients due to their long-term indwelling capability, versatility in drug administration, and flexibility. PICCs infection are a relatively common occurrence, yet there were no reported instances that it can metastasise to the lumbar spine.

Case summary: This case report describes a breast cancer patient who developed a methicillin-resistant Staphylococcus aureus lumbar vertebral infection secondary to a PICC-related infection during chemotherapy. Following PICC removal, bacterial culture confirmed the presence of highly virulent methicillin-resistant Staphylococcus aureus. The patient presented with fever and severe lumbar pain. Lumbar magnetic resonance imaging revealed paraspinal muscle edema from L1 to L3 with abnormal signal intensity in the affected regions, suggestive of vertebral osteomyelitis. Prompt initiation of appropriate antibiotic therapy based on the culture results led to significant improvement in the patient's lumbar pain.

Conclusion: This case highlights the importance of vigilant infection prevention and control measures to minimize the risk of PICC-related complications, such as bloodstream infections and subsequent metastatic infections.

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腰部耐甲氧西林金黄色葡萄球菌感染引起的周围插入中心导管：1例报告。

背景：外周中心导管（PICCs）由于其长期留置、给药的通用性和灵活性而被广泛应用于乳腺癌患者的化疗。PICCs感染是一种相对常见的发生，但没有报道的例子，它可以转移到腰椎。病例总结：本病例报告描述了一位乳腺癌患者在化疗期间继发picc相关感染，并发耐甲氧西林金黄色葡萄球菌腰椎感染。PICC去除后，细菌培养证实存在高毒力耐甲氧西林金黄色葡萄球菌。病人表现为发热和严重的腰痛。腰椎磁共振成像显示L1至L3椎旁肌肉水肿，受累区域信号强度异常，提示椎体骨髓炎。根据培养结果及时开始适当的抗生素治疗可显著改善患者的腰痛。结论：本病例强调了警惕感染预防和控制措施的重要性，以尽量减少picc相关并发症的风险，如血流感染和随后的转移性感染。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Clinical Cases Medicine-General Medicine

自引率

0.00%

发文量

3384

期刊介绍： The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.