[Hungarian adaptation of a questionnaire assessing the quality of life in patients with polycystic ovary syndrome].

Abstract

Introduction: Polycystic ovary syndrome is the most common endocrine disorder among women of reproductive age, affecting metabolic health, appearance and psychosocial well-being. To assess the impact of polycystic ovary syndrome on quality of life, it is essential to use disease-specific measurement tools, which are not widely available in Hungarian. Objective: Our study aimed to adapt the Hungarian version of the Polycystic Ovary Syndrome Quality of Life scale and to evaluate its psychometric properties. We examined the differences in the quality of life between patients with polycystic ovary syndrome and healthy controls. Furthermore, we explored the relationship between body mass index, negative affect, body image concerns and polycystic ovary syndrome-related quality of life. Method: Data were collected online from April to October 2024 (n = 854). In addition to demographic variables, the following questionnaires were administered: Polycystic Ovary Syndrome Quality of Life scale, World Health Organization Quality-of-Life Scale, Body Image Concern Inventory, and Depression, Anxiety and Stress Scale. Results: Confirmatory factor analysis confirmed the original four-factor structure. The healthy control group showed significantly higher scores in physical and psychological health, environment, and overall quality of life. The mediation analysis indicated that BMI and negative affect have a negative impact on polycystic ovary syndrome specific quality of life, which is partially mediated by body image concerns. Discussion: Our findings confirm the four-factor structure of the Polycystic Ovary Syndrome Quality of Life Scale. Women with polycystic ovary syndrome reported lower quality of life across multiple dimensions compared to healthy controls. The mediation analysis highlights the complex interactions between metabolic, endocrine and psychological factors, emphasizing the need for a multidisciplinary approach. Conclusion: Based on our results, the Hungarian version of the Polycystic Ovary Syndrome Quality of Life scale is a reliable and valid tool for assessing disease-specific quality of life. Orv Hetil. 2025; 166(27): 1060–1069.