Mastoid Signal Change and Acute Cerebral Venous Sinus Thrombosis: Unlocking the Puzzle.

IF 1.9 4区医学 Q3 CLINICAL NEUROLOGY

Annals of Indian Academy of Neurology Pub Date : 2025-07-07 DOI:10.4103/aian.aian_99_25

Ayush Agarwal, Venugopalan Y Vishnu, Meena Chandu, Divyani Garg, Manjari Agarwal, Ranjot Kaur, Maneesh Shakywar, Rohit Bhatia, Achal K Srivastava, Ashish Upadhyay, Ajay Garg, Mv Padma Srivastava

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引用次数: 0

Abstract

Abstract: Mastoid signal changes on magnetic resonance imaging in cerebral venous sinus thrombosis (CVT) patients are often misinterpreted as septic CVT. Studies have revealed mastoid signal changes in CVT patients. We conducted this study to investigate this relationship. Single-center, retrospective, observational study. Patients aged ≥18 years with venography-proven CVT were enrolled, excluding those with sepsis-induced CVT. Mastoid changes and clot burden score (CBS) were calculated. We screened and enrolled 128 and 124 CVT patients, respectively. Seventy per cent of patients had mastoid signal changes. The median mastoid score and CBS were 1 and 3, respectively. CBS was higher in CVT patients with mastoid changes. A higher CBS was associated with a higher mastoid score ( P = 0.003). Logistic regression analysis revealed an odds ratio of 0.67 (95% confidence interval: 0.52-0.87) for this association. The presence of radiological mastoid involvement is not sine qua non of associated middle ear infections and should raise the possibility of CVT.

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乳突信号改变与急性脑静脉窦血栓形成：解开谜团。

摘要：脑静脉窦血栓形成（CVT）患者磁共振成像乳突信号改变常被误诊为感染性CVT。研究发现CVT患者的乳突信号改变。我们进行这项研究是为了调查这种关系。单中心回顾性观察性研究。年龄≥18岁、经静脉造影证实的CVT患者入组，不包括脓毒症引起的CVT患者。计算乳突变化及凝块负荷评分（CBS）。我们分别筛选并入组了128例和124例CVT患者。70%的患者有乳突信号改变。乳突评分和CBS的中位数分别为1和3。伴有乳突改变的CVT患者CBS较高。较高的CBS与较高的乳突评分相关（P = 0.003）。Logistic回归分析显示，这种关联的优势比为0.67（95%可信区间：0.52-0.87）。影像学上乳突受累并不是相关中耳感染的必要条件，应提高CVT的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Indian Academy of Neurology Nervous System Diseases-

CiteScore

2.20

自引率

11.80%

发文量

293

审稿时长

29 weeks

期刊介绍： The journal has a clinical foundation and has been utilized most by clinical neurologists for improving the practice of neurology. While the focus is on neurology in India, the journal publishes manuscripts of high value from all parts of the world. Journal publishes reviews of various types, original articles, short communications, interesting images and case reports. The journal respects the scientific submission of its authors and believes in following an expeditious double-blind peer review process and endeavors to complete the review process within scheduled time frame. A significant effort from the author and the journal perhaps enables to strike an equilibrium to meet the professional expectations of the peers in the world of scientific publication. AIAN believes in safeguarding the privacy rights of human subjects. In order to comply with it, the journal instructs all authors when uploading the manuscript to also add the ethical clearance (human/animals)/ informed consent of subject in the manuscript. This applies to the study/case report that involves animal/human subjects/human specimens e.g. extracted tooth part/soft tissue for biopsy/in vitro analysis.