Can crayfish serve as bioindicator of environmental impact after exposure to Bisphenol A?

IF 4.2 3区环境科学与生态学 Q2 ENVIRONMENTAL SCIENCES

Environmental toxicology and pharmacology Pub Date : 2025-07-05 DOI:10.1016/j.etap.2025.104756

Aysel Çağlan Günal , Pinar Arslan Yuce , Marilena Briglia , Caterina Faggio

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引用次数: 0

Abstract

Bisphenol-A (BPA), is one of the industrial chemicals used mainly in the production of polycarbonates and epoxy resins, also known as endocrine disruptor and contaminant in aquatic ecosystems. Therefore, the present study aimed to determine the sublethal effects of BPA on the narrow-clawed crayfish, in terms of haemolymph parameters and histopathological changes after 24 and 96 h exposure times. The study was conducted in semi-static bioassays with 1.14 and 0.114 mg/L BPA concentrations. The total haemocyte counts significantly decreased in the 24 h exposed to BPA (p < 0.05). The lactate, glucose, and calcium values of haemolymph were significantly increased in the BPA-exposed groups (p < 0.05). The gills and the hepatopancreas tissues of the species revealed histopathological alterations at 1.14 mg/L following exposure to BPA in both exposure durations. The results of the study showed that the BPA can affect the health status of aquatic organisms via physiology and histopathology even at sublethal levels at acute exposure times.

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小龙虾是否可以作为双酚A暴露后环境影响的生物指标？

双酚a （BPA）是一种主要用于生产聚碳酸酯和环氧树脂的工业化学品，也被称为内分泌干扰物和水生生态系统污染物。因此，本研究旨在确定BPA在暴露24和96 h后对窄爪小龙虾的亚致死效应，包括血淋巴参数和组织病理学变化。该研究采用半静态生物测定法，BPA浓度分别为1.14和0.114 mg/L。总血细胞计数在暴露于BPA的24 h内显著降低（p <； 0.05）。bpa暴露组血淋巴乳酸、葡萄糖和钙值显著升高（p <； 0.05）。当BPA浓度为1.14 mg/L时，鱼鳃和肝胰腺组织在两种暴露时间内均出现组织病理学改变。研究结果表明，即使在亚致死水平的急性暴露时间下，双酚a也会通过生理和组织病理学影响水生生物的健康状况。

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来源期刊

Environmental toxicology and pharmacology 医学-毒理学

CiteScore

7.00

自引率

4.70%

发文量

185

审稿时长

34 days

期刊介绍： Environmental Toxicology and Pharmacology publishes the results of studies concerning toxic and pharmacological effects of (human and veterinary) drugs and of environmental contaminants in animals and man. Areas of special interest are: molecular mechanisms of toxicity, biotransformation and toxicokinetics (including toxicokinetic modelling), molecular, biochemical and physiological mechanisms explaining differences in sensitivity between species and individuals, the characterisation of pathophysiological models and mechanisms involved in the development of effects and the identification of biological markers that can be used to study exposure and effects in man and animals. In addition to full length papers, short communications, full-length reviews and mini-reviews, Environmental Toxicology and Pharmacology will publish in depth assessments of special problem areas. The latter publications may exceed the length of a full length paper three to fourfold. A basic requirement is that the assessments are made under the auspices of international groups of leading experts in the fields concerned. The information examined may either consist of data that were already published, or of new data that were obtained within the framework of collaborative research programmes. Provision is also made for the acceptance of minireviews on (classes of) compounds, toxicities or mechanisms, debating recent advances in rapidly developing fields that fall within the scope of the journal.