A prospective study of bladder volume assessment using ultrasound in prostate cancer radiotherapy: Comparison with cone-beam computed tomography (CBCT)

IF 2.5 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Radiography Pub Date : 2025-07-07 DOI:10.1016/j.radi.2025.103016

B. Bąk , K. Kaczmarek , D. Radoła , T. Winiecki , T. Bajon

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引用次数: 0

Abstract

Introduction

Prostate cancer radiotherapy requires consistent bladder filling to optimize dose delivery and minimize toxicity. This prospective study evaluated the accuracy of ultrasound (US) in bladder volume assessment compared to Cone Beam Computed Tomography (CBCT).

Methods

22 prostate cancer patients treated with a total dose of 50 Gy in 2 Gy fractions (25 fractions) between August and December 2019 using volumetric arc therapy (VMAT). Prior to initial CT (iCT) scans and during radiotherapy patients consumed 600–800 ml (3–4 cups) of water. Daily ultrasound measurements were taken to determine the mean bladder volume (USGRT) before Cone Beam Computed Tomography (CBCT) imaging, where the radiation therapist contoured the bladder on CBCT scans, calculating bladder volume with a 2 mm margin.

Results

A total of 1650 ultrasound measurements were performed. Statistical analysis included the Wilcoxon rank test and Spearman correlation to compare bladder volumes. The mean bladder volume measured by the US was 286 ml (SD ± 118), while CBCT recorded 241 ml (SD ± 124), with a strong correlation (r = 0.888, p < 0.001). The coefficient between USGRT and V2CBCT was r = 0.84 (p < 0.0001), indicating a significant correlation.

Conclusion

The Echoson® bladder scanner showed potential as a non-invasive alternative for daily bladder volume monitoring, reducing radiation exposure and streamlining treatment workflows. The bladder filling protocol is suitable for all patients, with a clinically acceptable measurement error of 17 %.

Implications for practice

Ultrasound enhances daily IGRT verification while minimizing radiation dose from CBCT.

查看原文本刊更多论文

超声在前列腺癌放疗中膀胱体积评估的前瞻性研究：与锥束计算机断层扫描（CBCT）的比较

前列腺癌放射治疗需要一致的膀胱填充以优化剂量传递和最小化毒性。这项前瞻性研究评估了超声（US）在膀胱容量评估中的准确性，并与锥束计算机断层扫描（CBCT）进行了比较。方法2019年8月至12月，22例前列腺癌患者采用体积弧治疗（VMAT），总剂量为50 Gy，分2 Gy （25 Gy）次治疗。在初始CT （iCT）扫描之前和放疗期间，患者消耗600-800毫升（3-4杯）水。在锥形束计算机断层扫描（CBCT）成像之前，每天进行超声测量以确定平均膀胱体积（USGRT），放射治疗师在CBCT扫描上勾画膀胱轮廓，计算膀胱体积，并以2mm的边缘计算膀胱体积。结果共进行了1650次超声测量。统计分析采用Wilcoxon秩检验和Spearman相关性来比较膀胱容量。美国膀胱容积平均值为286 ml (SD±118)，CBCT为241 ml (SD±124)，两者相关性较强(r = 0.888, p <；0.001)。USGRT与V2CBCT之间的系数r = 0.84 (p <；0.0001)，表明相关性显著。结论Echoson®膀胱扫描仪作为日常膀胱容量监测的无创替代方案，具有减少辐射暴露和简化治疗流程的潜力。膀胱填充方案适用于所有患者，临床可接受的测量误差为17%。超声增强每日IGRT验证，同时最大限度地减少CBCT的辐射剂量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiography RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

4.70

自引率

34.60%

发文量

169

审稿时长

63 days

期刊介绍： Radiography is an International, English language, peer-reviewed journal of diagnostic imaging and radiation therapy. Radiography is the official professional journal of the College of Radiographers and is published quarterly. Radiography aims to publish the highest quality material, both clinical and scientific, on all aspects of diagnostic imaging and radiation therapy and oncology.