A prospective study of bladder volume assessment using ultrasound in prostate cancer radiotherapy: Comparison with cone-beam computed tomography (CBCT)
IF 2.5 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
B. Bąk , K. Kaczmarek , D. Radoła , T. Winiecki , T. Bajon
{"title":"A prospective study of bladder volume assessment using ultrasound in prostate cancer radiotherapy: Comparison with cone-beam computed tomography (CBCT)","authors":"B. Bąk , K. Kaczmarek , D. Radoła , T. Winiecki , T. Bajon","doi":"10.1016/j.radi.2025.103016","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Prostate cancer radiotherapy requires consistent bladder filling to optimize dose delivery and minimize toxicity. This prospective study evaluated the accuracy of ultrasound (US) in bladder volume assessment compared to Cone Beam Computed Tomography (CBCT).</div></div><div><h3>Methods</h3><div>22 prostate cancer patients treated with a total dose of 50 Gy in 2 Gy fractions (25 fractions) between August and December 2019 using volumetric arc therapy (VMAT). Prior to initial CT (iCT) scans and during radiotherapy patients consumed 600–800 ml (3–4 cups) of water. Daily ultrasound measurements were taken to determine the mean bladder volume (USGRT) before Cone Beam Computed Tomography (CBCT) imaging, where the radiation therapist contoured the bladder on CBCT scans, calculating bladder volume with a 2 mm margin.</div></div><div><h3>Results</h3><div>A total of 1650 ultrasound measurements were performed. Statistical analysis included the Wilcoxon rank test and Spearman correlation to compare bladder volumes. The mean bladder volume measured by the US was 286 ml (SD ± 118), while CBCT recorded 241 ml (SD ± 124), with a strong correlation (r = 0.888, p < 0.001). The coefficient between USGRT and V2CBCT was r = 0.84 (p < 0.0001), indicating a significant correlation.</div></div><div><h3>Conclusion</h3><div>The Echoson® bladder scanner showed potential as a non-invasive alternative for daily bladder volume monitoring, reducing radiation exposure and streamlining treatment workflows. The bladder filling protocol is suitable for all patients, with a clinically acceptable measurement error of 17 %.</div></div><div><h3>Implications for practice</h3><div>Ultrasound enhances daily IGRT verification while minimizing radiation dose from CBCT.</div></div>","PeriodicalId":47416,"journal":{"name":"Radiography","volume":"31 5","pages":"Article 103016"},"PeriodicalIF":2.5000,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiography","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1078817425001609","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction
Prostate cancer radiotherapy requires consistent bladder filling to optimize dose delivery and minimize toxicity. This prospective study evaluated the accuracy of ultrasound (US) in bladder volume assessment compared to Cone Beam Computed Tomography (CBCT).
Methods
22 prostate cancer patients treated with a total dose of 50 Gy in 2 Gy fractions (25 fractions) between August and December 2019 using volumetric arc therapy (VMAT). Prior to initial CT (iCT) scans and during radiotherapy patients consumed 600–800 ml (3–4 cups) of water. Daily ultrasound measurements were taken to determine the mean bladder volume (USGRT) before Cone Beam Computed Tomography (CBCT) imaging, where the radiation therapist contoured the bladder on CBCT scans, calculating bladder volume with a 2 mm margin.
Results
A total of 1650 ultrasound measurements were performed. Statistical analysis included the Wilcoxon rank test and Spearman correlation to compare bladder volumes. The mean bladder volume measured by the US was 286 ml (SD ± 118), while CBCT recorded 241 ml (SD ± 124), with a strong correlation (r = 0.888, p < 0.001). The coefficient between USGRT and V2CBCT was r = 0.84 (p < 0.0001), indicating a significant correlation.
Conclusion
The Echoson® bladder scanner showed potential as a non-invasive alternative for daily bladder volume monitoring, reducing radiation exposure and streamlining treatment workflows. The bladder filling protocol is suitable for all patients, with a clinically acceptable measurement error of 17 %.
Implications for practice
Ultrasound enhances daily IGRT verification while minimizing radiation dose from CBCT.
RadiographyRADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
4.70
自引率
34.60%
发文量
169
审稿时长
63 days
期刊介绍:
Radiography is an International, English language, peer-reviewed journal of diagnostic imaging and radiation therapy. Radiography is the official professional journal of the College of Radiographers and is published quarterly. Radiography aims to publish the highest quality material, both clinical and scientific, on all aspects of diagnostic imaging and radiation therapy and oncology.