Numerical study of nasal hair effects on breathing comfort and particle deposition in a simplified vestibule region.

IF 3 3区 医学 Q2 BIOPHYSICS
Hasan Fatahi, Alireza Dastan, Sasan Sadrizadeh, Omid Abouali
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Abstract

Nasal hairs, often overlooked in human respiratory system studies, can be a decisive factor in maintaining respiratory health. Vibrissae can capture a certain range of particle sizes due to their filtering function, while they may also contribute to more breathing resistance. In this study, the role of nasal hairs in particle filtration and pressure drop within the nasal vestibule was investigated using computational fluid dynamics (CFD) simulations. Seven nasal hair specifications were examined in simplified human nasal vestibule models under steady laminar flow conditions at two airflow rates of 10 and 15 L/min. The deposition of microparticles in the simulated geometries was also numerically studied. The simulation results showed that the investigated nasal hairs lead to about a 2-20 Pa increase in the pressure drop, depending on the hair specifications and airflow rates. The associated growth in nasal resistance could potentially influence breathing comfort. Additionally, nasal hair was shown to enhance particle filtration, with the deposition fraction of particles correlating with the projected area of the hairs on a normal plane to the flow direction, which goes up by an increase in the number of hairs or their length. These findings clarify the significance of nasal hairs in the respiratory system and aim to balance the trade-off between improved particle filtration and increased breathing resistance due to nasal hairs. The acquired knowledge can be used in recommendations to different individuals regarding nasal hair trimming based on their health conditions.

鼻毛对简化前庭区域呼吸舒适性及颗粒沉积影响的数值研究。
鼻毛在人体呼吸系统研究中经常被忽视,但它却是维持呼吸系统健康的决定性因素。由于它们的过滤功能,触须可以捕获一定范围的颗粒大小,同时它们也可能有助于增加呼吸阻力。本研究采用计算流体动力学(CFD)模拟研究了鼻毛在颗粒过滤和鼻前庭压降中的作用。在稳定层流条件下,在10和15 L/min两种气流速率下,对简化的人类鼻前庭模型进行了7种鼻毛规格的测试。对模拟几何形状中微粒的沉积进行了数值研究。仿真结果表明,根据鼻毛规格和气流速率的不同,所研究的鼻毛导致压降增加约2-20 Pa。鼻阻力的增加可能会影响呼吸的舒适度。此外,鼻毛被证明可以增强颗粒过滤,颗粒的沉积分数与毛发在法向平面上的投影面积与流动方向相关,随着毛发数量或长度的增加而增加。这些发现阐明了鼻毛在呼吸系统中的重要性,旨在平衡改善颗粒过滤和鼻毛增加呼吸阻力之间的权衡。所获得的知识可用于根据个人的健康状况向不同的人建议修剪鼻毛。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomechanics and Modeling in Mechanobiology
Biomechanics and Modeling in Mechanobiology 工程技术-工程:生物医学
CiteScore
7.10
自引率
8.60%
发文量
119
审稿时长
6 months
期刊介绍: Mechanics regulates biological processes at the molecular, cellular, tissue, organ, and organism levels. A goal of this journal is to promote basic and applied research that integrates the expanding knowledge-bases in the allied fields of biomechanics and mechanobiology. Approaches may be experimental, theoretical, or computational; they may address phenomena at the nano, micro, or macrolevels. Of particular interest are investigations that (1) quantify the mechanical environment in which cells and matrix function in health, disease, or injury, (2) identify and quantify mechanosensitive responses and their mechanisms, (3) detail inter-relations between mechanics and biological processes such as growth, remodeling, adaptation, and repair, and (4) report discoveries that advance therapeutic and diagnostic procedures. Especially encouraged are analytical and computational models based on solid mechanics, fluid mechanics, or thermomechanics, and their interactions; also encouraged are reports of new experimental methods that expand measurement capabilities and new mathematical methods that facilitate analysis.
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