Comparison of Snowman and Single-Plug Circular Osteochondral Allograft Transplantation Techniques for Similarly Sized Defects: A Matched Cohort Analysis

Yusuf N. Mufti, Jared P. Sachs, Chloe H. Franzia, Fatima Bouftas, Kyle Wagner, Eric J. Cotter, Brian J. Cole
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Abstract

Background: Multiplug “snowman” osteochondral allograft transplantation (OCA) is an effective treatment method for large, irregularly shaped osteochondral defects of the knee. No existing literature directly compares the effectiveness of this technique with traditional single-plug circular OCA. Purpose: To compare failure rates, reoperation rates, and relevant patient-reported outcome (PRO) scores at 2-year follow-up between patients undergoing snowman OCA and patients undergoing single-plug OCA. Study Design: Case series; Level of evidence, 3. Methods: Patients who underwent snowman or single-plug OCA between 2001 and 2021 with a minimum 2-year follow-up were identified. Propensity score matching at 1:2 was performed based on age, sex, body mass index, defect location, and defect size. The PRO measures assessed included the International Knee Documentation Committee subjective score, Lysholm score, Knee Injury and Osteoarthritis Outcome Score, and 12-Item Short Form Health Survey. Failure was defined as conversion to arthroplasty, revision OCA, or graft degeneration on second-look arthroscopic examination. Additionally, rates of achieving the minimal clinically important difference (MCID) or patient acceptable symptom state (PASS) for PRO measures were determined. Results: There were 26 patients (mean age, 33.3 ± 9.3 years; 65.4% male) who underwent snowman OCA with a mean follow-up of 5.8 ± 4.1 years. No significant differences in baseline variables were identified compared with a matched control group of 52 patients who underwent single-plug OCA. No differences were detected in the rate of achieving the MCID or PASS between the groups for any PRO measure. Overall, 5 patients (19.2%) in the snowman group experienced graft failure at a mean 1.7 ± 1.0 years, while 10 patients (19.2%) in the single-plug group met the criteria for failure at a mean 6.6 ± 3.5 years. No differences were detected in the rate of failure or reoperations between the 2 groups. Conclusion: Multiplug “snowman” and single-plug circular OCA techniques yielded comparable clinical outcomes and graft survivorship for defects of a similar size in a matched cohort analysis. Defect shape, rather than size alone, should guide the selection of a technique. The snowman technique is advantageous for longer or oval-shaped defects not easily treated with a single plug, as it minimizes the removal of healthy cartilage while maintaining optimal outcomes.
雪人和单塞圆形骨软骨同种异体移植技术对相似大小缺陷的比较:匹配队列分析
背景:多塞“雪人”同种异体骨软骨移植(OCA)是治疗膝关节大而不规则骨软骨缺损的有效方法。没有现有文献直接比较该技术与传统的单塞圆形OCA的有效性。目的:比较雪人OCA和单塞OCA患者2年随访时的失败率、再手术率和相关患者报告预后(PRO)评分。研究设计:病例系列;证据水平,3。方法:对2001年至2021年间接受雪人或单塞OCA的患者进行至少2年的随访。根据年龄、性别、身体质量指数、缺陷位置和缺陷大小进行1:2的倾向评分匹配。评估的PRO措施包括国际膝关节文献委员会主观评分、Lysholm评分、膝关节损伤和骨关节炎结局评分以及12项简短健康调查。失败的定义是关节镜检查时转换为关节置换术、翻修OCA或移植物退变。此外,还确定了PRO测量中达到最小临床重要差异(MCID)或患者可接受症状状态(PASS)的比率。结果:26例患者,平均年龄33.3±9.3岁;65.4%男性)接受雪人OCA,平均随访5.8±4.1年。与52例接受单塞OCA的匹配对照组相比,基线变量无显著差异。在任何PRO测量中,两组之间达到MCID或PASS的比率均未发现差异。总体而言,雪人组5例(19.2%)患者平均在1.7±1.0年出现移植物失败,而单塞组10例(19.2%)患者平均在6.6±3.5年达到失败标准。两组手术失败率和再手术率均无差异。结论:在匹配的队列分析中,多塞“雪人”和单塞圆形OCA技术在相似大小缺陷的临床结果和移植物存活率方面具有可比性。缺陷的形状,而不是尺寸,应该指导技术的选择。雪人技术有利于较长的或椭圆形的缺陷,不容易用单个塞治疗,因为它最大限度地减少了健康软骨的移除,同时保持最佳效果。
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