Moussa Diop, Youssouph Coulibaly, Omar Thiaw, Abdoulaye Kane Dia, Yaya Ibrahim Coulibaly, Modibo Sangaré, Ndèye Aita Ndoye, Moussa Diallo, Mame Fatou Tall, Mouhamadou Bassir Faye, Oumar Ciss, Seynabou Mocote Diédhiou, Ousmane Faye, Abdoulaye Diop, Abdoulaye Konaté, Badara Samb, Abdoulaye Niang, Lassana Konaté, Roger Clément Kouly Tine, El Hadji Amadou Niang
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引用次数: 0
Abstract
Background: Malaria remains a public health problem in many African countries. In Senegal, the Southern region had the highest malaria incidence and malaria-related deaths. The relationship between vector density and malaria transmission remains poorly understood in some specific areas. The aim of this study was to characterize the current entomological and transmission parameters with special emphasis on the Anopheles gambiae complex in the malaria pre-elimination area of Mlomp south-western Senegal.
Methods: The study was conducted from July 2020 to February 2021 in Djicomol and Cadjinolle in the commune of Mlomp region of Ziguinchor, Senegal. Sampling was carried out using Human Landing Catches (HLC) and Pyrethrum Spray Catches (PSC). Ovaries were dissected to determine female parity rate. Infection status, blood meal sources and species molecular identification were determined using Enzyme-Linked Immunosorbent Assay (ELISA) and Polymerase Chain Reaction (PCR) techniques respectively.
Results: A total of 6956 mosquitoes of the An. gambiae complex were collected, of which 6739 were by HLC (96.88%) and 217 by PSC (3.12%). The mean human biting rate was 36.98 bites/person/night (b/p/n) indoors and 43.25 b/p/n outdoors. Female biting activity was more frequent during the second half of the night. Mean parity rates were 24.83% indoors and 18.94% outdoors. The human blood index was estimated at 76.09%. Overall, An. gambiae sensu stricto (s.s.) was the most common species (75.08%). No female An. gambiae was found to be infected with Plasmodium falciparum in the sub-sample tested, thus no malaria transmission was recorded in Mlomp during the study period.
Conclusions: The results alert malaria control programme to develop additional strategies for controlling these vectors, which show exophagic behaviours to effectively combat malaria.
背景：疟疾在许多非洲国家仍然是一个公共卫生问题。在塞内加尔，南部地区的疟疾发病率和与疟疾有关的死亡人数最高。在一些特定地区，对病媒密度与疟疾传播之间的关系仍然知之甚少。本研究的目的是表征目前的昆虫学和传播参数，特别强调在塞内加尔西南部mlompp疟疾消除前地区的冈比亚按蚊复群。方法：研究于2020年7月至2021年2月在塞内加尔Ziguinchor地区mmlomp公社的Djicomol和Cadjinolle进行。使用人类着陆捕集物（HLC）和除虫菊喷雾捕集物（PSC）进行取样。解剖卵巢以确定女性胎次率。分别采用酶联免疫吸附试验（ELISA）和聚合酶链反应（PCR）技术检测感染状况、血粉来源和菌种分子鉴定。结果：共捕获蚊虫6956只。共收集冈比亚菌络合物，其中hplc检出6739株（96.88%），PSC检出217株（3.12%）。人平均咬人率为室内36.98人/夜（b/p/n），室外43.25人/夜（b/p/n）。雌性的咬人活动在后半夜更为频繁。平均胎次率为室内24.83%，室外18.94%。人体血液指数估计为76.09%。总的来说,一个。窄感冈比亚（Gambiae sensu stricto, s.s.）最常见，占75.08%。没有女性安。在测试的亚样本中发现冈比亚感染了恶性疟原虫，因此在研究期间没有记录到疟疾传播。结论：研究结果提示疟疾控制规划制定更多的策略来控制这些表现出外噬行为的媒介，以有效防治疟疾。
期刊介绍：
Malaria Journal is aimed at the scientific community interested in malaria in its broadest sense. It is the only journal that publishes exclusively articles on malaria and, as such, it aims to bring together knowledge from the different specialities involved in this very broad discipline, from the bench to the bedside and to the field.
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