Sophia MV Schermerhorn , Afif N. Kulaylat , Donald J. Lucas
{"title":"Biliary dyskinesia in the pediatric population","authors":"Sophia MV Schermerhorn , Afif N. Kulaylat , Donald J. Lucas","doi":"10.1016/j.sempedsurg.2025.151503","DOIUrl":null,"url":null,"abstract":"<div><div>Biliary dyskinesia (BD) is a functional gallbladder disorder increasingly diagnosed in pediatric patients and a leading indication for laparoscopic cholecystectomy (LC). The pathophysiology remains unclear despite its prevalence, with gallbladder dysmotility and inflammation implicated. Diagnostic challenges arise from a lack of validated pediatric criteria and inconsistent hepatobiliary iminodiacetic acid (HIDA) scan technique and interpretation. LC is effective for symptom resolution with low complication rates, but medical management, including proton pump inhibitors, demonstrates variable success. This review highlights the need for prospective studies to refine diagnostic criteria, identify predictors of treatment success, and compare treatment strategies to improve outcomes for children with BD.</div></div>","PeriodicalId":49543,"journal":{"name":"Seminars in Pediatric Surgery","volume":"34 ","pages":"Article 151503"},"PeriodicalIF":1.4000,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminars in Pediatric Surgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1055858625000344","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Biliary dyskinesia (BD) is a functional gallbladder disorder increasingly diagnosed in pediatric patients and a leading indication for laparoscopic cholecystectomy (LC). The pathophysiology remains unclear despite its prevalence, with gallbladder dysmotility and inflammation implicated. Diagnostic challenges arise from a lack of validated pediatric criteria and inconsistent hepatobiliary iminodiacetic acid (HIDA) scan technique and interpretation. LC is effective for symptom resolution with low complication rates, but medical management, including proton pump inhibitors, demonstrates variable success. This review highlights the need for prospective studies to refine diagnostic criteria, identify predictors of treatment success, and compare treatment strategies to improve outcomes for children with BD.
期刊介绍:
Seminars in Pediatric Surgery provides current state-of-the-art reviews of subjects of interest to those charged with the surgical care of young patients. Each bimontly issue addresses a single topic with articles written by the experts in the field. Guest editors, all noted authorities, prepare each issue.