Raw bioelectrical impedance parameters as informative markers of body composition in youth

IF 7.4 2区医学 Q1 NUTRITION & DIETETICS

Clinical nutrition Pub Date : 2025-06-25 DOI:10.1016/j.clnu.2025.06.018

Gil B. Rosa , Ruben Francisco , Analiza M. Silva , Henry C. Lukaski , Ana V. Bernardino , Luís B. Sardinha

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引用次数: 0

Abstract

Background & Aims

Raw bioelectrical impedance analysis (BIA) parameters, particularly phase angle (PhA), are essential clinical and performance markers. However, their potential as body composition markers remains underexplored in youth. This investigation examined the associations between PhA and other series- and parallel-transformed raw BIA parameters and multiple body components organized at the molecular, cellular, and tissue levels in youth.

Methods

A cross-sectional sample of 681 youth (10–17 years, 49 % females) was assessed using a phase-sensitive BIA device (50 kHz), dual-energy X-ray absorptiometry, and a freezing point depression osmometer. Multiple linear regression examined each raw BIA parameter's unadjusted and adjusted relationships with body components.

Results

PhA was associated with all body components in females (molecular level: β = |0.170| to |0.584|; cellular level: β = 0.409 to 0.582; tissue level: β = 0.170 to 0.569) and males (molecular level: β = |0.542| to |0.729|; cellular level: β = 0.612 to 0.729; tissue level: β = 0.714; p ≤ 0.05), independently of relevant confounders. No relationship was found between PhA and fat mass and adipose tissue in males (p > 0.05). Other raw BIA parameters were shown to be even more associated with body composition than PhA in females (molecular level: β = |0.172| to |0.827|; cellular level: β = |0.292| to |0.713|; tissue level: β = |0.635| to |0.821|) and males (molecular level: β = |0.555| to |0.926|; cellular level: β = |0.554| to |0.870|; tissue level: β = |0.827| to |0.916|; p ≤ 0.05). In both sexes, the association power of these BIA parameters was lower regarding fat-related parameters (β = non-significant to |0.460|).

Conclusions

PhA was moderately associated with most body components in youth, except for fat-related components in males, independent of confounding variables. Resistance adjusted to stature consistently emerged as the most relevant marker, highlighting its potential to inform about body composition at an early age.

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原始生物电阻抗参数作为青少年身体组成的信息标记

背景,目的生物阻抗分析（BIA）参数，特别是相角（PhA）是临床和性能的重要指标。然而，它们作为身体成分标记的潜力在青少年中仍未得到充分发掘。本研究考察了PhA与其他串联和并联转化的原始BIA参数之间的关系，以及青年在分子、细胞和组织水平上组织的多种身体成分。方法采用相敏BIA仪（50 kHz）、双能x线吸收仪和冰点下降渗透仪对681名10-17岁青年（49%为女性）的横断面样本进行评估。多元线性回归检验了每个原始BIA参数与身体成分的未调整和调整关系。结果spha与女性机体各组分均相关(分子水平：β = |0.170| ~ |0.584|；细胞水平：β = 0.409 ~ 0.582；组织水平：β = 0.170 ~ 0.569)，男性(分子水平：β = |0.542 ~ |0.729|；细胞水平：β = 0.612 ~ 0.729；组织水平：β = 0.714；P≤0.05)，与相关混杂因素无关。在男性中，PhA与脂肪量和脂肪组织没有关系(p >；0.05)。其他原始BIA参数与女性体成分的相关性甚至高于PhA(分子水平：β = |0.172|至|0.827|；细胞水平：β = |0.292| ~ |0.713|；组织水平：β = |0.635| ~ |0.821|)，男性(分子水平：β = |0.555| ~ |0.926|；细胞水平：β = |0.554| ~ |0.870|；组织水平：β = |0.827| ~ |0.916|；P≤0.05)。在两性中，这些BIA参数与脂肪相关参数的关联能力较低（β =不显著至|0.460|）。结论青年spha与除男性脂肪相关成分外的大多数身体成分存在中度相关性，不受混杂变量的影响。与身高相适应的抵抗力一直是最相关的指标，突出了它在早期告知身体成分的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical nutrition 医学-营养学

CiteScore

14.10

自引率

6.30%

发文量

356

审稿时长

28 days

期刊介绍： Clinical Nutrition, the official journal of ESPEN, The European Society for Clinical Nutrition and Metabolism, is an international journal providing essential scientific information on nutritional and metabolic care and the relationship between nutrition and disease both in the setting of basic science and clinical practice. Published bi-monthly, each issue combines original articles and reviews providing an invaluable reference for any specialist concerned with these fields.