Air pollution and respiratory diseases in conurbated cities in the state of São Paulo.

Luiz Fernando Costa Nascimento, Ana Clara Silva Raposo de Almeida, Julia Ferreira Gomes Pereira, Mariana Telles de Castro, Adriana Oliveira Ribeiro Dos Santos
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Abstract

Objective: To estimate the association between exposure to particulate matter with less than 10u of aerodynamic diameter (PM10) and hospital admissions due to acute respiratory diseases in children.

Methods: This is an ecological time series study with data on hospitalizations for respiratory diseases in children living in the conurbated cities of Taubaté, Tremembé, and Pindamonhangaba located in the Vale do Paraíba in São Paulo. Hospital admission data refer to the period between January 1, 2016 and December 31, 2019. Information on hospital admissions was obtained from the DATASUS database, and concentration values (μg/m3) of the pollutant PM10, temperature, and humidity relative air were obtained from the Environmental Company of the State of São Paulo. Negative binomial regression was used. Population attributable fraction and hospitalization costs were estimated.

Results: A total of 1,291 hospitalizations were identified in the conurbated municipalities with a daily average of 0.88 standard deviation (±) 1.06, varying between 0-7 hospitalizations. Significant exposures to PM10 can be observed at all lags, except the four-day lag (Lag 4). The total cost of hospitalizations was around US$ 800,000.00 and the excess number of hospitalizations (135) represented an expense of around US$ 80,000.00.

Conclusions: Studies with conurbated cities are easily applicable, extending the study area. The results reinforce the harmful role of exposure to air pollutants in children's health.

圣保罗州大城市的空气污染和呼吸系统疾病。
目的:评估空气动力学直径小于10u的颗粒物(PM10)暴露与儿童急性呼吸系统疾病住院率之间的关系。方法:这是一项生态时间序列研究,收集了居住在圣保罗do Vale Paraíba的taubat、ttremb和Pindamonhangaba等大城市的儿童因呼吸道疾病住院的数据。住院数据为2016年1月1日至2019年12月31日期间。入院信息来自DATASUS数据库,污染物PM10浓度值(μg/m3)、相对空气温度和湿度来自圣保罗州环境公司。采用负二项回归。估计人口归因分数和住院费用。结果:在大城市共发现1,291例住院,平均每日0.88标准差(±)1.06,在0-7之间变化。除4天滞后期(滞后期4)外,在所有滞后期均可观察到显著的PM10暴露。住院总费用约为80万美元,多住院人数(135人)的费用约为80万美元。结论:以大城市为研究对象的研究易于适用,扩大了研究范围。研究结果进一步表明,接触空气污染物对儿童健康有害。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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