The Aorta-Gonad-Mesonephros (AGM): A Crossroads Between Hematopoiesis and Angiogenesis. A Historical Note.

IF 2.3 4区医学 Q1 ANATOMY & MORPHOLOGY

Clinical Anatomy Pub Date : 2025-07-04 DOI:10.1002/ca.70001

Domenico Ribatti

引用次数: 0

Abstract

The aorta-gonad-mesonephros (AGM) is a region of embryonic mesoderm that develops during embryonic development from the para-aortic splanchnopleura in chick, mouse, and human embryos. The AGM contains the dorsal aorta, genital ridges, and mesonephros, and lies between the notochord and the somatic mesoderm. The aim of this historical note was to underline the fundamental role of AGM in the development of the hematopoietic system at the crossroads between endothelial and hematopoietic cells.

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主动脉-性腺-中肾（AGM）：造血和血管生成的十字路口。历史笔记。

主动脉-性腺-中肾（AGM）是鸡、小鼠和人类胚胎在胚胎发育过程中从主动脉旁胸膜发育而来的胚胎中胚层的一个区域。AGM包括背主动脉、生殖脊和中肾，位于脊索和躯体中胚层之间。这篇历史笔记的目的是强调AGM在造血系统发展中的基本作用，在内皮细胞和造血细胞之间的十字路口。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Anatomy 医学-解剖学与形态学

CiteScore

5.50

自引率

12.50%

发文量

154

审稿时长

3 months

期刊介绍： Clinical Anatomy is the Official Journal of the American Association of Clinical Anatomists and the British Association of Clinical Anatomists. The goal of Clinical Anatomy is to provide a medium for the exchange of current information between anatomists and clinicians. This journal embraces anatomy in all its aspects as applied to medical practice. Furthermore, the journal assists physicians and other health care providers in keeping abreast of new methodologies for patient management and informs educators of new developments in clinical anatomy and teaching techniques. Clinical Anatomy publishes original and review articles of scientific, clinical, and educational interest. Papers covering the application of anatomic principles to the solution of clinical problems and/or the application of clinical observations to expand anatomic knowledge are welcomed.