Clinical application of preoperative volumetric measurement for interventional precise embolization in the treatment of hypersplenism caused by liver cirrhosis.

IF 1.6 3区 医学 Q2 SURGERY
Yin-Bao Hu, Lei Duan, Guang-Yu Liu, Xiao-Ming Wang
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引用次数: 0

Abstract

Objective: Volume measurement software is not routinely utilized in clinical practice before splenic artery embolization. To explore the function of such software measurement in this context, we conducted a retrospective study.

Methods: We divided patients into two groups: 38 patients in Group A underwent three-dimensional reconstruction using Revolution CT, and 37 patients in Group B underwent imaging with normal CT technology. We compared the changes in liver function test results and haematological parameters between these two groups.

Results: A total of 75 patients who underwent splenic artery embolization from January 2018 to January 2023 were included. The preoperative baseline data were not significantly different (all P values > 0.05). Both groups showed improvements in liver function and hypersplenism-related parameters. Within 2 weeks after surgery, Group A had significantly greater WBC (5.54 ± 1.92 × 10^9/L) and PLT (65.80 ± 20.12 × 10^9/L) counts than Group B (WBC: 4.14 ± 1.96 × 10^9/L; PLT: 52.70 ± 14.78 × 10^9/L; P < 0.05), indicating better control of hypersplenism. At 2 months postintervention, Group A demonstrated more favourable improvements in postintervention splenic volume (reduced from 1045 ± 122.9 cm³ to 489.5 ± 84.93 cm³), portal vein diameter (from 1.51 ± 0.19 cm to 1.28 ± 0.13 cm), and portal vein flow velocity (increased from 17.70 ± 5.25 cm/s to 23.56 ± 6.40 cm/s) than Group B. Moreover, a 53.2% splenic volume reduction was noted in Group A, which was significantly greater than the 31.4% reduction in Group B. Additionally, Group A had fewer adverse reactions, with lower liver/gastrointestinal toxicity (χ²=4.242, P = 0.039) and fever severity (χ²= 4.805, P = 0.028).

Conclusions: This study suggests that using Revolution CT prior to splenic artery embolization provides an effective method for managing hypersplenism, enhancing liver function, and reducing the risk of complications.

术前容积测量介入精准栓塞治疗肝硬化脾功能亢进的临床应用。
目的:脾动脉栓塞前体积测量软件在临床应用中并不常见。为了探讨这种软件测量在这种情况下的作用,我们进行了回顾性研究。方法:将患者分为两组,A组38例行Revolution CT三维重建,B组37例行正常CT成像。我们比较两组患者肝功能检查结果和血液学参数的变化。结果:2018年1月至2023年1月,共纳入75例脾动脉栓塞患者。术前基线资料差异无统计学意义(P值均为0.05)。两组患者肝功能和脾功能亢进相关指标均有改善。术后2周内,A组WBC(5.54±1.92 × 10^9/L)和PLT(65.80±20.12 × 10^9/L)计数明显高于B组(WBC: 4.14±1.96 × 10^9/L;拟合系数:52.70±14.78 × 10^9/ l;结论:本研究提示在脾动脉栓塞前使用Revolution CT是治疗脾功能亢进、增强肝功能、降低并发症风险的有效方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMC Surgery
BMC Surgery SURGERY-
CiteScore
2.90
自引率
5.30%
发文量
391
审稿时长
58 days
期刊介绍: BMC Surgery is an open access, peer-reviewed journal that considers articles on surgical research, training, and practice.
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