Nonpharmacological Interventions Prevent Delirium in Older Adult Surgical Patients: A Network Meta-Analysis of Randomized Controlled Trials.

IF 1.1 4区医学 Q4 GERIATRICS & GERONTOLOGY

Journal of gerontological nursing Pub Date : 2025-09-01 Epub Date: 2025-07-07 DOI:10.3928/00989134-20250626-01

José Lucas Sena da Silva, Lorena Azi, Kan Ding, Luiz Eduardo Ritt, Juliana Caldas

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引用次数: 0

Abstract

Purpose: The current meta-analysis aimed to evaluate the effectiveness of nonpharmacological interventions in preventing delirium among older adult surgical patients.

Method: Randomized controlled trials (RCTs) examining nonpharmacological approaches were selected. A meta-analysis was performed using random-effect models to calculate standard mean differences and 95% confidence intervals (CI).

Findings: Twelve RCTs (N = 3,829) met inclusion criteria. Nonpharmacological interventions significantly reduced delirium incidence (OR [odds ratio] = 0.57, 95% CI [0.49, 0.66]). Multicomponent (OR = 0.6, 95% CI [0.49, 0.75]) and single-component (OR = 0.53, 95% CI [0.42, 0.66]) interventions were effective. Network meta-analysis revealed that the multicomponent intervention "Family HELP" demonstrated significant superiority over four other interventions (OR = 0.11, 95% CI [0.04, 0.33]; p-score = 0.911).

Conclusion: Nonpharmacological interventions were found to effectively prevent delirium among older adult surgical patients, with the Family HELP intervention being the most effective. These interventions should be integrated into nursing care guidelines to enhance patient-centered care and experience.

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非药物干预预防老年外科患者谵妄：随机对照试验的网络荟萃分析。

目的：本荟萃分析旨在评估非药物干预在预防老年外科患者谵妄中的有效性。方法：选择随机对照试验（rct）检验非药物治疗方法。采用随机效应模型进行meta分析，计算标准均值差异和95%置信区间（CI）。结果：12项rct （N = 3829）符合纳入标准。非药物干预显著降低谵妄发生率（OR[优势比]= 0.57,95% CI[0.49, 0.66]）。多组分（OR = 0.6, 95% CI[0.49, 0.75]）和单组分（OR = 0.53, 95% CI[0.42, 0.66]）干预是有效的。网络荟萃分析显示，多成分干预“Family HELP”比其他四种干预具有显著优势(OR = 0.11, 95% CI [0.04, 0.33]；P-score = 0.911)。结论：非药物干预可有效预防老年外科患者谵妄，其中Family HELP干预效果最好。这些干预措施应纳入护理指南，以加强以患者为中心的护理和经验。老年护理杂志，xx(xx), xx-xx。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of gerontological nursing 医学-护理

CiteScore

2.00

自引率

7.70%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal of Gerontological Nursing is a monthly, peer-reviewed journal publishing clinically relevant original articles on the practice of gerontological nursing across the continuum of care in a variety of health care settings, for more than 40 years.