Trends in publicly and privately prescribed anxiolytics in Croatia: do we need a new regulatory framework.

IF 1.5 Q3 PHARMACOLOGY & PHARMACY
Marta Kučan Štiglić, Tea Strbad, Andrej Belančić, Jasenka Mršić Pelčić, Dinko Vitezić
{"title":"Trends in publicly and privately prescribed anxiolytics in Croatia: do we need a new regulatory framework.","authors":"Marta Kučan Štiglić, Tea Strbad, Andrej Belančić, Jasenka Mršić Pelčić, Dinko Vitezić","doi":"10.1093/ijpp/riaf051","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The study aimed to analyse changes in the prescribing trends of anxiolytics in Croatia over the past 15 years, focusing on changes in prescribing patterns and the average cost per defined daily dose (DDD) and to evaluate how frequently patients covered by the Croatian Health Insurance Fund (CHIF) received private prescriptions for anxiolytics.</p><p><strong>Methods: </strong>Data on total consumption of anxiolytics in Croatia were obtained from two sources: the IMS database and the CHIF database for the period from 2006 to 2022.</p><p><strong>Key findings: </strong>The total usage of anxiolytic drugs increased from 61.13 DDD/1000 in 2006 to 82.78 DDD/1000 in 2022, an increase of 35.42%, while the financial expenditure in the same period decreased by 15.57%. Diazepam is the anxiolytic drug with the highest prescription rate, with an increase of 67.42%. The highest increase overall was in the total consumption of alprazolam, despite a decrease from 21.22% in 2011 to 16.53% in 2022 in private prescriptions, indicating a substantial increase in prescriptions covered by insurers.</p><p><strong>Conclusions: </strong>Despite being either not recommended by clinical guidelines or of doubtful efficacy in many cases, prescribing of anxiolytics is common. There is a noticeable increase in anxiolytic drug use in Croatia during the investigated period, while the total financial expenditure has decreased due to price pressure on medications imposed by the national insurer. The high rate of private prescription of anxiolytics is observed. An enhanced national regulatory framework for prescribing anxiolytics in Croatia is needed.</p>","PeriodicalId":14284,"journal":{"name":"International Journal of Pharmacy Practice","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pharmacy Practice","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/ijpp/riaf051","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0

Abstract

Objectives: The study aimed to analyse changes in the prescribing trends of anxiolytics in Croatia over the past 15 years, focusing on changes in prescribing patterns and the average cost per defined daily dose (DDD) and to evaluate how frequently patients covered by the Croatian Health Insurance Fund (CHIF) received private prescriptions for anxiolytics.

Methods: Data on total consumption of anxiolytics in Croatia were obtained from two sources: the IMS database and the CHIF database for the period from 2006 to 2022.

Key findings: The total usage of anxiolytic drugs increased from 61.13 DDD/1000 in 2006 to 82.78 DDD/1000 in 2022, an increase of 35.42%, while the financial expenditure in the same period decreased by 15.57%. Diazepam is the anxiolytic drug with the highest prescription rate, with an increase of 67.42%. The highest increase overall was in the total consumption of alprazolam, despite a decrease from 21.22% in 2011 to 16.53% in 2022 in private prescriptions, indicating a substantial increase in prescriptions covered by insurers.

Conclusions: Despite being either not recommended by clinical guidelines or of doubtful efficacy in many cases, prescribing of anxiolytics is common. There is a noticeable increase in anxiolytic drug use in Croatia during the investigated period, while the total financial expenditure has decreased due to price pressure on medications imposed by the national insurer. The high rate of private prescription of anxiolytics is observed. An enhanced national regulatory framework for prescribing anxiolytics in Croatia is needed.

克罗地亚公共和私人处方抗焦虑药的趋势:我们是否需要一个新的监管框架?
目的:本研究旨在分析克罗地亚过去15年来抗焦虑药处方趋势的变化,重点关注处方模式的变化和每限定日剂量的平均费用,并评估克罗地亚健康保险基金(CHIF)承保的患者接受抗焦虑药私人处方的频率。方法:2006年至2022年期间克罗地亚抗焦虑药物总消费量数据来自两个来源:IMS数据库和CHIF数据库。重点发现:抗焦虑药物总使用量从2006年的61.13 DDD/1000增加到2022年的82.78 DDD/1000,增长35.42%,同期财政支出下降15.57%。安定是处方率最高的抗焦虑药物,增加了67.42%。整体增幅最高的是阿普唑仑的总消费量,尽管私人处方从2011年的21.22%下降到2022年的16.53%,表明保险公司承保的处方大幅增加。结论:尽管临床指南不推荐或在许多情况下疗效可疑,抗焦虑药的处方是常见的。在调查期间,克罗地亚抗焦虑药物的使用明显增加,而由于国家保险公司对药品施加价格压力,财政支出总额减少。私人处方抗焦虑药的比例较高。克罗地亚需要加强抗焦虑药处方的国家监管框架。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
2.90
自引率
5.60%
发文量
146
期刊介绍: The International Journal of Pharmacy Practice (IJPP) is a Medline-indexed, peer reviewed, international journal. It is one of the leading journals publishing health services research in the context of pharmacy, pharmaceutical care, medicines and medicines management. Regular sections in the journal include, editorials, literature reviews, original research, personal opinion and short communications. Topics covered include: medicines utilisation, medicine management, medicines distribution, supply and administration, pharmaceutical services, professional and patient/lay perspectives, public health (including, e.g. health promotion, needs assessment, health protection) evidence based practice, pharmacy education. Methods include both evaluative and exploratory work including, randomised controlled trials, surveys, epidemiological approaches, case studies, observational studies, and qualitative methods such as interviews and focus groups. Application of methods drawn from other disciplines e.g. psychology, health economics, morbidity are especially welcome as are developments of new methodologies.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信