Reducing anxiety symptoms in adolescents with pre-existing depression: results from a randomized control trial.

IF 3.2 3区医学 Q2 PSYCHIATRY

Frontiers in Psychiatry Pub Date : 2025-06-19 eCollection Date: 2025-01-01 DOI:10.3389/fpsyt.2025.1461887

Henriette Solberg, Thormod Idsoe, Serap Keles

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引用次数: 0

Abstract

Introduction: Depression and anxiety have a long history of co-occurrence, with a relatively high prevalence in the Norwegian population both separate and combined. In adolescence, this prevalence increases significantly and may impact youths' social and academic functioning drastically. Having effective treatments aimed at adolescents may have potential to prevent both short and long-term effects associated with these disorders. The aim of the current study was to examine whether the "Adolescent Coping with Depression Course" (ACDC), a cognitive behaviour therapy (CBT)-based group intervention aimed at adolescents with subclinical mild-to-moderate depressive symptoms, would also be effective in reducing anxiety symptoms.

Methods: Data, which came from a two-arm parallel cluster randomised control trial conducted in Norway, were collected from 228 adolescents, 133 of whom were assigned to the 14-week ACDC intervention and 95 were assigned to the usual care condition. The data were analysed with structural equation modelling.

Results: The results indicated that the intervention is effective in reducing anxiety symptoms via reducing the depressive symptoms, thus illustrating an indirect effect.

Discussion: The findings suggested that ACDC has the potential to reduce anxiety symptoms over time through its effect on depressive symptoms. Implications of the results are presented.

Clinical trial registration: https://www.isrctn.com, identifier ISRCTN19700389.

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减轻已有抑郁症的青少年的焦虑症状：一项随机对照试验的结果

前言：抑郁和焦虑共存的历史很长，在挪威人口中，无论是单独还是合并，患病率都相对较高。在青春期，这种流行率显著增加，并可能极大地影响青少年的社会和学术功能。针对青少年的有效治疗可能有可能预防与这些疾病相关的短期和长期影响。当前研究的目的是检验“青少年应对抑郁课程”（ACDC），一种基于认知行为疗法（CBT）的群体干预，针对有亚临床轻至中度抑郁症状的青少年，是否也能有效减轻焦虑症状。方法：数据来自于在挪威进行的一项双臂平行集群随机对照试验，收集了228名青少年的数据，其中133人被分配到14周的ACDC干预组，95人被分配到常规护理组。采用结构方程模型对数据进行分析。结果：干预可通过减轻抑郁症状而有效减轻焦虑症状，说明干预具有间接作用。讨论：研究结果表明，随着时间的推移，ACDC有可能通过其对抑郁症状的作用来减轻焦虑症状。提出了研究结果的意义。临床试验注册：https://www.isrctn.com，标识符ISRCTN19700389。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Psychiatry Medicine-Psychiatry and Mental Health

CiteScore

6.20

自引率

8.50%

发文量

2813

审稿时长

14 weeks

期刊介绍： Frontiers in Psychiatry publishes rigorously peer-reviewed research across a wide spectrum of translational, basic and clinical research. Field Chief Editor Stefan Borgwardt at the University of Basel is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. The journal''s mission is to use translational approaches to improve therapeutic options for mental illness and consequently to improve patient treatment outcomes.