First Cases of Dengue Fever Confirmed in the National Hospitals of Zinder and Niamey.

IF 1 Q4 INFECTIOUS DISEASES
Case Reports in Infectious Diseases Pub Date : 2025-06-26 eCollection Date: 2025-01-01 DOI:10.1155/crdi/6694128
Doutchi Mahamadou, Adamou Lagare, Moussa Sahada, Adamou Bara Abdoul-Aziz, Mahaman Moustapha Lamine, Souleymane Adoum Fils, Bagnou Hamsatou, Hamidou Issa Hama, George Thomas, Ramatou Hamidou Lazoumar, Garba Abdoul Aziz, Adehossi Eric
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引用次数: 0

Abstract

Dengue is an emerging arbovirus infection caused by any of the four serotypes of dengue virus (DENV-1, DENV-2, DENV-3, and DENV-4) and transmitted via the bite of a mosquito from the genus Aedes. We hereby report seven cases of dengue hospitalized at the infectious and tropical disease departments of the National Hospitals of Zinder and Niamey from October 22, 2023, to December 05, 2023. All the cases presented fever, vomiting, algic, and hemorrhagic syndrome. Results from the complete blood count analysis revealed that all the patients had thrombocytopenia, six cases have leukopenia and two cases have anemia. Furthermore, one case of kidney failure was recorded. The case confirmation was conducted at the National Reference Laboratory for Arbovirus on blood samples using qualitative Real-Time Polymerase Chain Reaction (qRT-PCR). The technic is based on the amplification of any of the four serotypes of dengue virus nucleic acid using specific primers and probes as described by Wagner et al. All the cases recovered after hospitalization.

津德尔和尼亚美国家医院确诊首例登革热病例。
登革热是由登革热病毒四种血清型(DENV-1、DENV-2、DENV-3和DENV-4)中的任何一种引起的新出现的虫媒病毒感染,并通过伊蚊属蚊子的叮咬传播。兹报告从2023年10月22日至2023年12月5日在津德尔和尼亚美国立医院传染病科和热带病科住院的7例登革热病例。所有病例均出现发热、呕吐、疼痛和出血性综合征。全血细胞计数分析结果显示,所有患者均有血小板减少症,6例有白细胞减少症,2例有贫血。此外,还记录了1例肾衰竭。该病例在虫媒病毒国家参考实验室使用定性实时聚合酶链式反应(qRT-PCR)对血液样本进行了确认。该技术基于使用Wagner等人描述的特定引物和探针扩增四种登革热病毒核酸血清型中的任何一种。所有病例住院后均康复。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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