Marléne Baumeister, Merle Munko, Kai-Philipp Gladow, Marc Ditzhaus, Nayden Chakarov, Markus Pauly
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引用次数: 0
Abstract
In medical, ecological, and psychological research, there is a need for methods to handle multiple testing, for example, to consider group comparisons with more than two groups. Typical approaches that deal with multiple testing are mean- or variance-based which can be less effective in the context of heavy-tailed and skewed data. Here, the median is the preferred measure of location and the interquartile range (IQR) is an adequate alternative to the variance. Therefore, it may be fruitful to formulate research questions of interest in terms of the median or the IQR. For this reason, we compare different inference approaches for two-sided and noninferiority hypotheses formulated in terms of medians or IQRs in an extensive simulation study. We consider multiple contrast testing procedures combined with a bootstrap method as well as testing procedures with Bonferroni correction. As an example of a multiple testing problem based on heavy-tailed data, we analyze an ecological trait variation in early and late breeding in a medium-sized bird of prey.
期刊介绍:
Biometrical Journal publishes papers on statistical methods and their applications in life sciences including medicine, environmental sciences and agriculture. Methodological developments should be motivated by an interesting and relevant problem from these areas. Ideally the manuscript should include a description of the problem and a section detailing the application of the new methodology to the problem. Case studies, review articles and letters to the editors are also welcome. Papers containing only extensive mathematical theory are not suitable for publication in Biometrical Journal.