The Combined Use of Acute Regional and Interventional Pain Offers Superior Quality of Life in Palliative Care.

Pain medicine case reports Pub Date : 2024-01-01
Tolga Suvar, Stephen Music, Matthew Tan, Neal Mehta
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Abstract

Background: Pain is a common symptom associated with cancer and can greatly compromise quality of life, motivation, and further treatments. Intrathecal pump (ITP) offers improved pain scores and clinical outcomes, while reducing the adverse effects of systemic analgesics.

Case report: A 29-year-old woman with neurofibromatosis type 1 had a malignant peripheral nerve sheath tumor in her right thigh surgically resected. However, one month later, metastatic lesions were found throughout her body. Despite chemotherapy, the disease spread and pain became severe resulting in multiple hospitalizations and halting treatment. Multimodal analgesia was pursued, including regional anesthesia, but she was unable to tolerate the adverse effects of systemic opioids. For long-term analgesia, ITP was pursued, which significantly improved her pain control and quality of life.

Conclusions: In advanced stages of cancer, we highlight the significant benefits ITP offers with improved quality of life and reduced medication side-effect profiles vs systemic analgesics.

急性局部疼痛和介入性疼痛的联合使用在姑息治疗中提供了更高的生活质量。
背景:疼痛是与癌症相关的常见症状,可极大地影响生活质量、积极性和进一步治疗。鞘内泵(ITP)可改善疼痛评分和临床结果,同时减少全身镇痛药的不良反应。病例报告:一例29岁女性1型神经纤维瘤病右大腿周围神经鞘恶性肿瘤手术切除。然而,一个月后,她的全身出现了转移性病变。尽管进行了化疗,但疾病扩散,疼痛变得严重,导致多次住院和停止治疗。多模式镇痛,包括区域麻醉,但她不能忍受全身阿片类药物的不良反应。对于长期镇痛,采用ITP治疗,明显改善了患者的疼痛控制和生活质量。结论:在晚期癌症患者中,我们强调ITP与全身性镇痛药相比在改善生活质量和减少药物副作用方面的显著益处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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