In space fabrication of Janus base nano matrix for improved assembly and bioactivity.

IF 4.1 1区物理与天体物理 Q1 MULTIDISCIPLINARY SCIENCES

npj Microgravity Pub Date : 2025-07-02 DOI:10.1038/s41526-025-00482-z

Anne Yau, Maxwell Landolina, Mari Anne Snow, Pinar Mesci, Brandon Williams, James B Hoying, Jana Stoudemire, Rayyanah Barnawi, Peggy Whitson, Rose Hernandez, Derek Duflo, Honglu Wu, Yupeng Chen

引用次数: 0

Abstract

Nanomaterials have a broad impact on both space and biomedical research but have never been produced in-space for regenerative applications. During the Axiom-2 (Ax-2) mission, our team completed the first-ever low Earth orbit (LEO) manufacturing of Janus base nanomaterials (JBNs) for cartilage tissue regeneration. This fabrication of JBNs in LEO resulted in superior product homogeneity, stability, and loading ability compared to Earth samples, demonstrating the benefits of manufacturing in microgravity.

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在空间制备中改进Janus基纳米基质的组装和生物活性。

纳米材料对空间和生物医学研究具有广泛的影响，但从未在空间中生产用于再生应用。在Axiom-2 （Ax-2）任务期间，我们的团队首次在近地轨道（LEO）制造了用于软骨组织再生的Janus基纳米材料（jbn）。与地球样品相比，在LEO中制造的jbn具有优越的产品均匀性、稳定性和装载能力，证明了在微重力下制造的好处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

npj Microgravity Physics and Astronomy-Physics and Astronomy (miscellaneous)

CiteScore

7.30

自引率

7.80%

发文量

审稿时长

9 weeks

期刊介绍： A new open access, online-only, multidisciplinary research journal, npj Microgravity is dedicated to publishing the most important scientific advances in the life sciences, physical sciences, and engineering fields that are facilitated by spaceflight and analogue platforms.