Postoperative Complications in Elderly Patients Undergoing Surgery for Ovarian Cancer: A NSQIP Analysis

IF 1.9 3区医学 Q3 ONCOLOGY

Journal of Surgical Oncology Pub Date : 2025-07-03 DOI:10.1002/jso.70034

Lina Salman, Allan Covens, Lilian T. Gien, Danielle Vicus

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Abstract

Background and Objectives

Elderly patients with ovarian cancer (OC) commonly receive modified treatment due to the assumption of higher risk. The aim of this study is to evaluate postoperative complications in elderly patients undergoing surgery for OC.

Methods

Retrospective cohort study of patients with OC identified in the NSQIP database, (2013–2021). Younger patients included 40–69 years old, and elderly patients were ≥ 70 years old. Major complications included: pulmonary embolism, deep vein thrombosis, acute kidney injury, stroke, cardiac arrest, space surgical site infection, myocardial infarction, sepsis, septic shock, and return to the operating room.

Results

Of the 11,108 patients, 8214 (74%) were in the younger patient and 2894 (26%) in the elderly patient group. Elderly patients had higher rates of postoperative pneumonia (2.6% vs. 1.2%), myocardial infarction (1.4% vs. 0.3%), and major complications (3.5% vs. 2.0%), p < 0.0001 for all. Discharge to rehab was higher in elderly patients (3.1% vs. 0.5%, p < 0.001). On multivariate logistic regression, older age was associated with “major complications” (aOR 1.79, 95% CI 1.38–2.31, p < 0.0001).

Conclusions

In OC patients selected for surgery, elderly patients are at higher risk of Postoperative complications and are less likely to be discharged home. This should be considered when counseling patients pre-operatively and planning for peri-operative care and disposition.

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老年卵巢癌术后并发症的NSQIP分析

背景与目的：老年卵巢癌（OC）患者由于风险较高，通常接受改良治疗。本研究的目的是评估老年OC手术患者的术后并发症。方法：回顾性队列研究在NSQIP数据库中发现的OC患者（2013-2021）。年轻患者年龄40-69岁，老年患者年龄≥70岁。主要并发症包括：肺栓塞、深静脉血栓形成、急性肾损伤、中风、心脏骤停、空间手术部位感染、心肌梗死、败血症、感染性休克、返回手术室等。结果：11108例患者中，年轻组8214例（74%），老年组2894例（26%）。老年患者术后肺炎（2.6% vs. 1.2%）、心肌梗死（1.4% vs. 0.3%）和主要并发症（3.5% vs. 2.0%）发生率较高。结论：在选择手术的OC患者中，老年患者发生术后并发症的风险较高，出院回家的可能性较小。在术前咨询患者和围手术期护理和处置计划时应考虑到这一点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Surgical Oncology 医学-外科

CiteScore

4.70

自引率

4.00%

发文量

367

审稿时长

2 months

期刊介绍： The Journal of Surgical Oncology offers peer-reviewed, original papers in the field of surgical oncology and broadly related surgical sciences, including reports on experimental and laboratory studies. As an international journal, the editors encourage participation from leading surgeons around the world. The JSO is the representative journal for the World Federation of Surgical Oncology Societies. Publishing 16 issues in 2 volumes each year, the journal accepts Research Articles, in-depth Reviews of timely interest, Letters to the Editor, and invited Editorials. Guest Editors from the JSO Editorial Board oversee multiple special Seminars issues each year. These Seminars include multifaceted Reviews on a particular topic or current issue in surgical oncology, which are invited from experts in the field.