Silver diamine fluoride treatment for the management of deep caries: A scoping review

IF 4.8 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of dentistry Pub Date : 2025-06-30 DOI:10.1016/j.jdent.2025.105946

Adam Sheridan, May Lei Mei, Paul R. Cooper, Trudy Milne, Lara T. Friedlander

{"title":"Silver diamine fluoride treatment for the management of deep caries: A scoping review","authors":"Adam Sheridan, May Lei Mei, Paul R. Cooper, Trudy Milne, Lara T. Friedlander","doi":"10.1016/j.jdent.2025.105946","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>Dental caries is a biofilm-driven, multifactorial disease that can progress to deep dentine lesions, risking pulp exposure and complications. Silver diamine fluoride (SDF) has emerged as a non-invasive approach for caries management. This scoping review assesses the available evidence on SDF’s effects in deep caries management, focusing on clinical success rates, pulp vitality, restoration outcomes, and patient acceptance.</div></div><div><h3>Data and sources</h3><div>A broad literature search of four electronic databases (PubMed, EMBASE, Medline, EMCARE) was conducted up to December 2024, focusing on <em>in vivo</em> studies published in English that investigated SDF application in deep caries. Reference lists of relevant articles were also screened.</div></div><div><h3>Article selection</h3><div>The initial search yielded 504 articles. Nineteen articles published up to December 2024 were included in the final review.</div></div><div><h3>Conclusion</h3><div>SDF shows considerable promise for deep caries treatment, with high rates of caries arrest, favourable pulp outcomes, and generally good patient acceptance. However, heterogeneity in study designs, lesion depth classifications, and reapplication protocols demonstrate the need for more standardised research. Future long-term investigations should further investigate the role of SDF in managing deep caries, particularly in vulnerable populations and resource-limited settings.</div></div><div><h3>Clinical Significance</h3><div>This scoping review provides a valuable overview of the range of potential factors that should be considered regarding SDF research on deep caries. Standardised clinical protocols and strategies to minimise staining could further improve its application and utility.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105946"},"PeriodicalIF":4.8000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of dentistry","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0300571225003902","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

Dental caries is a biofilm-driven, multifactorial disease that can progress to deep dentine lesions, risking pulp exposure and complications. Silver diamine fluoride (SDF) has emerged as a non-invasive approach for caries management. This scoping review assesses the available evidence on SDF’s effects in deep caries management, focusing on clinical success rates, pulp vitality, restoration outcomes, and patient acceptance.

Data and sources

A broad literature search of four electronic databases (PubMed, EMBASE, Medline, EMCARE) was conducted up to December 2024, focusing on in vivo studies published in English that investigated SDF application in deep caries. Reference lists of relevant articles were also screened.

Article selection

The initial search yielded 504 articles. Nineteen articles published up to December 2024 were included in the final review.

Conclusion

SDF shows considerable promise for deep caries treatment, with high rates of caries arrest, favourable pulp outcomes, and generally good patient acceptance. However, heterogeneity in study designs, lesion depth classifications, and reapplication protocols demonstrate the need for more standardised research. Future long-term investigations should further investigate the role of SDF in managing deep caries, particularly in vulnerable populations and resource-limited settings.

Clinical Significance

This scoping review provides a valuable overview of the range of potential factors that should be considered regarding SDF research on deep caries. Standardised clinical protocols and strategies to minimise staining could further improve its application and utility.

查看原文本刊更多论文

二胺氟化银治疗深部龋：范围综述。

目的：龋齿是一种生物膜驱动的多因素疾病，可发展为牙本质深部病变，有牙髓暴露和并发症的风险。二胺氟化银（SDF）已成为一种非侵入性的龋齿治疗方法。本综述评估了SDF在深部龋治疗中的作用，重点是临床成功率、牙髓活力、修复结果和患者接受度。数据和来源：截至2024年12月，我们对PubMed、EMBASE、Medline、EMCARE四个电子数据库进行了广泛的文献检索，重点是研究SDF在深部龋中的应用的英文体内研究。还筛选了相关文章的参考书目。文章选择：最初的搜索产生504篇文章。截止2024年12月发表的19篇文章被纳入最终评审。结论：SDF在深度龋病治疗中表现出相当大的希望，龋齿抑制率高，牙髓效果良好，患者接受度普遍较高。然而，研究设计、病变深度分类和再应用方案的异质性表明需要更多的标准化研究。未来的长期调查应进一步调查SDF在管理深部龋中的作用，特别是在脆弱人群和资源有限的环境中。临床意义：本综述对深度龋的SDF研究中应考虑的潜在因素范围进行了有价值的概述。标准化的临床方案和策略，以尽量减少染色可以进一步提高其应用和效用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of dentistry 医学-牙科与口腔外科

CiteScore

7.30

自引率

11.40%

发文量

349

审稿时长

35 days

期刊介绍： The Journal of Dentistry has an open access mirror journal The Journal of Dentistry: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. The Journal of Dentistry is the leading international dental journal within the field of Restorative Dentistry. Placing an emphasis on publishing novel and high-quality research papers, the Journal aims to influence the practice of dentistry at clinician, research, industry and policy-maker level on an international basis. Topics covered include the management of dental disease, periodontology, endodontology, operative dentistry, fixed and removable prosthodontics, dental biomaterials science, long-term clinical trials including epidemiology and oral health, technology transfer of new scientific instrumentation or procedures, as well as clinically relevant oral biology and translational research. The Journal of Dentistry will publish original scientific research papers including short communications. It is also interested in publishing review articles and leaders in themed areas which will be linked to new scientific research. Conference proceedings are also welcome and expressions of interest should be communicated to the Editor.